Table 1

Expected values and distribution parameters for the deterministic model and probabilistic sensitivity analyses

ParameterExpected value±SEDistribution
Study population2028 252±10%γ
Cost per B12 tablet$C0.16±0.008γ
Professional fee for dispensing tablets21$C11.93
Cost per B12 injectable dose21–23$C0.75
Cost for CBC and serum B12 analyses*$C6.50
Laboratory technician time for blood sample draw and analyses (hours)*0.75 (range 0.25–1)Triangular
Laboratory technician wage and benefits24*$C44.60 (range $C35.82–$C51.41)Triangular
Fee for administration of intramuscular injection in a physician's office26$C10.30
Cost for physician consultation visit26$C35.91
Fee for administration of intramuscular injection in a pharmacy27$C20.00
  • Normal distribution sample values probabilistically from a normal curve with specified mean (expected value) and SD. Triangular distribution sample values probabilistically within the range specified, with increasing probability as values near the expected value.

  • *Indicates parameter only included in year 1 of the model.

  • CBC, complete blood count.