Table 3

Cognitive test scores and composite domain scores at follow-up compared to baseline

Test variables	Raw scores		Z-scores and statistics
	IIH baseline	IIH follow-up
	n=31	n=29	Z*	95% CI	p Value
Executive function			−0.18	−0.77 to 0.42	0.16
Intra–extra dimensional set shift
ID/ED Errors^log	8.1 (0–32)	5.8 (1–32)	−0.82	−1.40 to −0.25	0.77
Total errors adjusted^log	20.9 (7–177)	14.4 (7–68)	−0.56	−1.14 to 0.01	0.26
Stockings of Cambridge
Solved in minimum moves	9.61 (2)	19.9 (2)	−0.08	−0.66 to 0.49	0.55
Initial thinking time^log, s	6.5 (2–18.3)	6.7 (2.5–18.4)	0.45	−0.14 to 1.02	0.98
Subsequent thinking time^log, s	0.013 (0–3.7)	0.013 (0–3.7)	0.11	−0.47 to 0.68	0.85
Trail Making Test†
Trail Making B-A^log, s	39.2 (14.7–101.1)	33.1 (1.3–79.5)	0.46	−0.12 to 1.05	0.002
Working memory			−0.33	−0.84 to 0.18	0.44
Spatial working memory
Strategy score^log	29.9 (20–42)	27.9 (19–42)	−0.24	−0.81 to 0.34	0.1
Total errors^log	10.2 (0–79)	10.1 (0–61)	−0.24	−0.81 to 0.34	0.5
Spatial span
Span length	6.4 (1.3)	6.4 (1.3)	−0.27	−0.85 to 0.31	0.96
Processing speed			−1.23	−1.83 to −0.64	0.49
Verbal Fluency†
Letters	19.4 (7.0)	18.6 (6.6)	−1.27	−1.86 to −0.69	0.88
Categories	39.8 (9.9)	42.5 (10.8)	−0.93	−1.51 to −0.34	0.41
Trail Making Test†
Trail Making A^log, s	31.5 (18.0–68.1)	32.9 (9.8)	−0.56	−1.15 to 0.02	0.95
Trail Making B^log, s	73.5 (40.9–169.2)	66.1 (38.7–125.4)	−0.18	−0.79 to 0.4	0.16
Symbol digit modalities
Correct symbols	47.8 (10.2)	49.1 (12.3)	−0.91	−1.49 to −0.33	0.5
Visuospatial memory			0.39	−0.17 to 1.02	0.0005
Rey-Osterrieth figure
Immediate recall, score	24.5 (5.4)	28.9 (4.1)	0.36	−0.22 to 0.93	0.002
Delayed recall, score	23.8 (5)	28.8 (3.8)	0.31	−0.26 to 0.89	0.0002
Attention
Rapid visual processing
A’ sensitivity to target	0.9 (0.1)	0.92 (0.04)	−0.14	−0.71 to 0.43	0.03
Reaction time			−1.31	−1.90 to −0.71	0.9
Reaction^log, ms	428.7 (264.9–988.6)	387.4 (393–710.1)	−1.45	−2.02 to −0.88	0.68
Movement, ms	417.8 (86.3)	412.3 (72.1)	−0.89	−1.46 to −0.31	0.32

Normally distributed raw score variables are shown as mean (SD). Logarithmically transformed variables^log are shown as arithmetic mean (range). Z-scores and test statistics are given in estimates from a linear mixed model adjusting for education and headache at the time of testing and multiple testing. Significant p values are printed in italic.
*Z Patients at follow-up compared to healthy controls.
†n=29, as Trail Making Test scores and Verbal Fluency scores from non-native Danish speakers (n=2) were omitted from analysis.
IIH, intracranial hypertension.