IIH baseline | IIH follow-up | Controls | Statistics | ||
---|---|---|---|---|---|
n=31 | n=29 | n=31 | p Value* | p Value† | |
Demographics | |||||
Age (SD), years | 31.0 (11.2) | 30.7 (11.2) | 0.91 | ||
Gender, f/m | 31/0 | 31/0 | |||
Danish adult reading test (SD), words | 22.9 (6.8) | 24.8 (5.3) | 0.15 | ||
Education (SD), years | 11.2 (2.2) | 12.8 (2.1) | 0.001 | ||
Educational level (n) | 0.38 | ||||
Long cycle higher (≥5 years) | 0 | 3 | |||
Medium cycle higher (3–5 years) | 4 | 7 | |||
Short cycle higher (<3 years) | 4 | 4 | |||
Vocational upper-secondary | 5 | 3 | |||
Student | 10 | 10 | |||
No education | 8 | 4 | |||
Household income (n) | 0.81 | ||||
High (>DKK 400 000/year) | 10 | 8 | |||
Middle (DKK 200–400 000/year) | 12 | 12 | |||
Low (<DKK 200 000/year) | 9 | 11 | |||
Clinical characteristics | |||||
BMI (SD), kg/m2 | 35.7 (6.2) | 34.0 (6) | 23.6 (4) | <0.001 | 0.009 |
Headache at time of testing, n (%) | 22.0 (71) | 14.0 (48) | 0 | ||
Mean headache intensity (SD), VAS | 2.64 (2.3) | 1.84 (2.4) | 0.01 | ||
ICP ↔ cognitive testing‡ (SD), days | 3.0 (2.4) | 1.0 (1.6) | |||
Mean ICP§ (SD), cm H2O | 41.0 (12.6) | 25.9 (5.5) | <0.001 | ||
Memory difficulties¶, n (%) | 17.0 (55) | 18.0 (62) | 0.42 | ||
Concentration difficulties¶, n (%) | 20.0 (65) | 15.0 (52) | 0.18 | ||
Duration of IIH symptoms (SD), months | 4.3 (5.4) |
χ2 Test was used for household income, Fisher's exact test for educational level and McNemar's test for paired categorical variables. Two-tailed t test was used for numerical variables. Significant p Values are printed in italic.
*p difference between patients at baseline and healthy controls.
†p difference between patients at baseline and follow-up.
‡Time span between ICP measurement and cognitive testing.
§ICP measured with direct ICP monitor (n=1) not included.
¶Subjective difficulties reported by the patients.
BMI, body mass index; DKK, Danish Krone; ICP, intracranial pressure; IIH, intracranial hypertension; VAS, visual analogue scale.