Predicted anthropometry across categories of maternal eating disorder, with adjustment for standard confounders (gestational age, maternal age, maternal education, parity) and potential mediators (maternal pre-pregnancy BMI and smoking during pregnancy)
| Boys | Girls | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean predicted anthropometry (SD) of offspring of unexposed women | Mean difference (SD) from unexposed for offspring of women with: | Mean predicted anthropometry (SD) of offspring of unexposed women | Mean difference (SD) from unexposed for offspring of women with: | |||||||
| Anorexia nervosa | Bulimia nervosa | Anorexia nervosa and Bulimia nervosa | Other psychiatric disorders | Anorexia nervosa | Bulimia nervosa | Anorexia nervosa and Bulimia nervosa | Other psychiatric disorders | |||
| Height (cm) | ||||||||||
| Birth | 50.3 (5.4) | +0.21 (2.0) | +0.17 (2.1) | +0.04 (2.0) | −0.13 (2.2)* | 49.8 (5.3) | −0.41 (1.9)* | −0.04 (2.1) | +0.30 (2.0) | −0.09 (2.2) |
| 1 year | 76.2 (5.4) | +0.40 (2.3)* | +0.05 (2.4) | +0.05 (2.4) | −0.219 (2.6)* | 74.3 (5.3) | −0.2 (2.4) | +0.09 (2.4) | −0.68 (2.4)* | −0.11 (2.6) |
| 2 years | 87.4 (5.4) | +0.47 (3.0)* | +0.01 (3.1) | +0.04 (3.0) | −0.25 (3.2)* | 85.7 (5.3) | −0.18 (3.0) | +0.06 (3.0) | −0.88 (3.0)* | −0.11 (3.2) |
| 5 years | 110.3 (6.8) | +0.47 (4.5) | +0.16 (4.5) | −0.04 (4.4) | −0.34 (4.7)* | 109.7 (6.0) | −0.25 (4.3) | −0.14 (4.3) | −0.88 (4.2) | −0.10 (4.6) |
| 10 years | 140.8 (8.8) | −0.64 (7.3) | +1.89 (7.5)*** | −0.665 (7.08) | −0.56 (7.9)* | 138.9 (8.6) | −0.52 (6.2) | −0.61 (6.9) | −0.26 (6.7) | −0.05 (7.5) |
| Ponderal index (kg/m3) | N=4537 | N=73 | N=84 | N=38 | N=496 | N=4363 | N=64 | N=81 | N=30 | N=424 |
| Birth | 26.2 (5.4) | −0.37 (2.49) | −0.29 (2.6) | +0.08 (2.5) | +0.11 (2.7) | 26.3 (5.3) | −0.12 (2.2) | +0.47 (2.2)** | −0.22 (2.2) | −0.07 (2.3) |
| 1 year | 23.4 (4.72) | −0.07 (2.14) | +0.39 (2.2)* | +0.28 (2.1) | +0.197 (2.3)** | 23.3 (5.3) | +0.34 (2.4) | +0.05 (2.5) | +0.35 (2.7) | −0.20 (2.7)* |
| BMI (kg/m2) | N=4271 | N=68 | N=78 | N=35 | N=452 | N=4117 | N=61 | N=78 | N=29 | N=398 |
| 2 years | 16.8 (3.92) | +0.19 (2.0) | +0.27 (2.0) | +0.33 (1.8) | +0.13 (2.0)* | 16.6 (3.9) | −0.26 (1.9) | +0.32 (1.9) | +0.37 (1.8) | −0.08 (2.1) |
| 5 years | 15.9 (3.92) | +0.43 (1.4)*** | +0.11 (1.4) | +0.51 (1.4)** | −0.05 (1.5) | 16.0 (3.9) | +0.08 (1.5) | +0.29 (1.5)* | +0.45 (1.5)* | +0.15 (1.6)** |
| 10 years | 17.7 (4.57) | +0.17 (3.2) | +0.11 (3.2) | +0.08 (3.2) | +0.06 (3.6) | 18.1 (5.1) | −0.09 (3.5) | −0.26 (3.4) | −0.39 (3.2) | +0.56 (3.7)*** |
Values are predicted from the multilevel models, and represent the predicted anthropometry for offspring of mean gestational age (39.4 weeks) and with a mother with the following characteristics: mean age (28.2 years), less than O-level education, parity of zero, mean prepregnancy BMI (22.94 kg/m2), non-smoker during pregnancy. P values are from Z-tests comparing each group to the offspring of women with no eating or other psychiatric disorder.
*p ≤ 0.1.
**p<0.05.
***p<0.01.
BMI, body mass index.