Effects of various continuous variables on annual FEV1 changes in stable patients with COPD (univariable analysis)
| Variables | rs | p Value |
|---|---|---|
| EMPs | ||
| VE-cadherin EMPs | −0.43 | 0.003 |
| E-selectin EMPs | −0.65 | <0.001 |
| PECAM EMPs | 0.03 | 0.834 |
| Age | 0.01 | 0.968 |
| Body mass index | −0.01 | 0.943 |
| LAA score | 0.02 | 0.819 |
| Pack-years smoking index | −0.002 | 0.988 |
| Leucocyte counts | −0.28 | 0.057 |
| C reactive protein | −0.03 | 0.838 |
| Serum amyloid A | −0.15 | 0.365 |
| D-dimer | −0.19 | 0.296 |
Bold typeface indicates statistical significance.
COPD, chronic obstructive pulmonary disease; EMPs, circulating endothelial microparticles; FEV1, forced expiratory volume in 1 s; LAA, low attenuation area; PECAM, platelet endothelial cell adhesion molecule; VE-cadherin, vascular endothelial-cadherin.