Overview of primary and secondary objectives of the AERIS study
| Level | Objective |
|---|---|
| Primary | ▸ To estimate the incidence rate of all-cause AECOPD ▸ To estimate the incidence rate of AECOPD having sputum containing bacterial pathogens (overall and by species) |
| Secondary | ▸ To describe the proportion of overall and specific bacterial pathogens detected in sputum by severity of AECOPD ▸ To describe the proportion of overall and specific bacterial pathogens detected in sputum in stable COPD ▸ To estimate the incidence rate of AECOPD having sputum containing viral pathogens (overall and by species) ▸ To describe the proportion of overall and specific viral pathogens detected in sputum by severity of AECOPD ▸ To estimate the time elapsed between consecutive AECOPD episodes ▸ To assess the impact of all-cause AECOPD and stable COPD on health-related quality of life ▸ To assess the impact on healthcare use: – Of all-cause AECOPD – Of AECOPD having sputum containing bacterial pathogens – Of AECOPD having sputum containing viral pathogens |
AECOPD, acute exacerbations of chronic obstructive pulmonary disease; AERIS, Acute Exacerbation and Respiratory InfectionS in COPD.