Table 5

Summary of regression analysis for biomarkers of exposure and effect of chlorpyrifos predicting average percentage of neurological symptoms by subclasses among applicators

Outcome variable (symptom subclass)	Unadjusted models Ln TCPy (mg/g Cr) (n=42)		Adjusted models Ln TCPy (mg/g Cr) (n=42)		Unadjusted models Ln (post-AChE/pre-AChE) (n=28)		Adjusted models Ln (post-AChE/pre-AChE) (n=28)		Unadjusted models Ln (post-BChE/pre-BChE) (n=29)		Adjusted models Ln (post-BChE/pre-BChE) (n=29)
Outcome variable (symptom subclass)	B (se)	p Value	B (se)	p Value	B (se)	p Value	B (se)	p Value	B (se)	p Value	B (se)	p Value
Behaviour and affect	2.16 (0.57)	<0.001	2.80 (0.91)	0.004	−12.59 (10.86)	0.26	−16.34 (16.04)	0.33	−6.96 (4.09)	0.10	−12.26 (5.73)	0.04
Autonomic	5.69 (0.75)	<0.001	3.24 (0.99)	0.002	−38.45 (14.88)	0.02	−4.84 (17.22)	0.78	−19.65 (5.42)	0.001	−9.69 (6.40)	0.14
Cognitive	6.92 (0.87)	<0.001	5.27 (1.34)	<0.001	−46.22 (17.49)	0.01	1.73 (20.82)	0.94	−24.16 (6.03)	0.001	−13.56 (7.55)	0.07
Motor	2.48 (0.49)	<0.001	1.67 (0.74)	0.03	−6.27 (8.41)	0.46	4.50 (12.03)	0.37	−5.75 (3.15)	0.08	−3.90 (4.64)	0.41
Sensory	6.47 (0.90)	<0.001	4.94 (1.34)	0.001	−27.49 (17.64)	0.13	−0.75 (22.46)	0.97	−20.00 (6.41)	0.004	−13.88 (8.86)	0.13
Temporary disability (non-specific)	5.48 (0.61)	<0.001	3.64 (0.78)	<0.001	−41.13 (14.14)	0.007	−10.74 (16.61)	0.53	−21.80 (4.73)	0.001	−13.52 (5.73)	0.03

*Regression models adjusted for field stations, age, family monthly income, pesticide use at home and average number of hours of work in the field over the entire application season (for applicators only).
AChE, acetylcholinesterase; BChE, butyrylcholinesterase; Cr, creatinine; TCPy, trichloro-2-pyridinol.