Characteristics of 242 patients with chronic myeloid leukaemia diagnosed September 2004–August 2011, distributed by vital status on 1 April 2013
| Diagnosed September 2004–August 2011 | Status 1 April 2013 | HRs (95% CI) | |||
|---|---|---|---|---|---|
| Total (N=242) | Alive (N=195) | Dead (N=47) | Unadjusted | Adjusted* | |
| N (%) | N (%) | N (%) | |||
| Age at diagnosis, years | |||||
| <60 | 132 (54.6) | 116 (59.8) | 16 (34.0) | 1.00 | 1.00 |
| ≥60 | 110 (45.4) | 79 (40.2) | 31 (66.0) | 2.59 (1.39 to 4.83) | 2.65 (1.42 to 4.96) |
| Sex | |||||
| Male | 145 (60.0) | 115 (59.0) | 30 (63.8) | 1.00 | 1.00 |
| Female | 97 (40.0) | 80 (41.0) | 17 (36.2) | 0.84 (0.46 to 1.52) | 0.67 (0.37 to 1.23) |
| Deprivation quintile | |||||
| 1–3 | 143 (59.1) | 124 (63.9) | 19 (40.4) | 1.00 | 1.00 |
| 4–5 (less affluent) | 98 (40.9) | 70 (36.1) | 28 (59.6) | 2.60 (1.45 to 4.66) | 3.43 (1.89 to 6.22) |
| Phase at presentation | |||||
| Chronic | 235 (97.1) | 192 (81.7) | 43 (18.3) | 1.00 | 1.00 |
| Accelerated/blast crisis | 7 (2.9) | 3 (42.9) | 4 (57.1) | 7.46 (2.61 to 21.28) | 22.93 (7.24 to 72.61) |
| Baseline cytogenetics | |||||
| Ph+ve only | 209 (86.4) | 173 (82.8) | 36 (17.2) | 1.00 | 1.00 |
| Variant Ph+ve | 18 (7.4) | 15 (83.3) | 3 (16.7) | 0.89 (0.27 to 2.88) | 1.12 (0.34 to 3.68) |
| Additional abnormality | 12 (5.0) | 6 (50.0) | 6 (50.0) | 3.96 (1.66 to 9.42) | 4.94 (2.03 to12.00) |
| Amplified Ph+ve | 3 (1.2) | 1 (33.3) | 2 (66.7) | 6.82 (1.63 to 28.46) | 13.61 (3.09 to 60.00) |
*Adjusted for all other characteristic in the Table except the one of interest and cytogenetics.