Variable | All patients | No CKD (62%) | CKD (38%) | p Value | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Observation | Mean/% | SD | Observation | Mean/% | SD | Observation | Mean/% | SD | ||
Male | 4041 | 51 | 2527 | 59 | 1514 | 38 | <0.0001 | |||
Age | 4041 | 71 | 11 | 2527 | 67 | 10 | 1514 | 77 | 9 | <0.0001 |
Diabetes duration | 4041 | 7.7 | 6.3 | 2527 | 6.6 | 5.6 | 1514 | 9.6 | 6.9 | <0.0001 |
HbA1c (%) | 3128 | 6.9 | 1.0 | 1930 | 6.9 | 1.1 | 1198 | 6.9 | 1.0 | 0.056 |
HbA1c (mmol/mol) | 3128 | 52 | 13 | 1930 | 52 | 13 | 1198 | 52 | 13 | 0.056 |
MDRD | 3260 | 72 | 23 | 1991 | 85 | 17 | 1269 | 52 | 17 | NA |
Severe decline | 4041 | 10.4 | 2527 | 7.5 | 1514 | 15.3 | <0.001 | |||
Per cent with ≥2 certain drop | 4041 | 18.3 | 2527 | 15.8 | 1514 | 22.5 | <0.001 | |||
LDL cholesterol | 2868 | 98 | 33 | 1823 | 100 | 33 | 1045 | 95 | 33 | <0.001 |
SBP | 2887 | 136 | 14 | 1848 | 135 | 14 | 1039 | 136 | 15 | 0.224 |
DBP | 2887 | 79 | 8 | 1848 | 80 | 8 | 1039 | 77 | 8 | <0.001 |
CVD | 4041 | 29.1 | 2527 | 22% | 1514 | 40% | <0.001 | |||
Smoking | 1254 | 14.7 | 816 | 17% | 438 | 10% | 0.001 | |||
Diabetes treatment | 4041 | 2527 | 1514 | |||||||
Lifestyle only | 1510 | 37.3% | 896 | 35% | 614 | 41% | ||||
OAD | 2013 | 49.8% | 1385 | 55% | 628 | 41% | <0.0001 | |||
Insulin | 518 | 12.8% | 246 | 10% | 272 | 18% | <0.0001 | |||
Antihypertensive | 4041 | 54.5% | 2527 | 51% | 1514 | 60% | <0.0001 | |||
ACE inhibitors | 4041 | 44.1% | 2527 | 42% | 1514 | 47% | 0.007 | |||
Platelet inhibition | 4041 | 39.6% | 2527 | 39% | 1514 | 41% | 0.145 | |||
Lipid lowering | 4041 | 48.1% | 2527 | 49% | 1514 | 46% | 0.046 | |||
Anaemia | 3927 | 3.5% | 2472 | 2.5% | 1455 | 5.2% | <0.001 | |||
Osteoporosis | 3927 | 4.2% | 2472 | 2.75% | 1455 | 6.75% | <0.001 | |||
Psychological distress | 3927 | 11.3% | 2472 | 10.5% | 1455 | 12.7% | 0.042 | |||
Dementia | 3927 | 1.3% | 2472 | 1.1% | 1455 | 1.7% | 0.107 | |||
Malignancy | 3927 | 7.1% | 2472 | 5.1% | 1455 | 10.5% | <0.001 | |||
Gout | 3927 | 8.0% | 2472 | 6.9% | 1455 | 9.9% | 0.001 |
CKD, chronic kidney disease; CVD, cardiovascular disease; DBP, diastolic blood pressure; HbA1c, glycated haemoglobin; LDL, low-density lipoprotein; MDRD, modification of diet in renal disease; OAD, oral antidiabetics; SBP, systolic blood pressure.