Additive interactions between SF (per 50 μg/L) and BMI (per 2 kg/m2)
| Parameters | Male | Female | Total estimates (95% CI) |
|---|---|---|---|
| Interaction model 1* | |||
| RERI | −0.003 (−0.022 to 0.491) | 0.895 (0.006 to 13.531) | 0.314 (0.026 to 1.506) |
| AP | −0.003 (−0.017 to 0.219) | 0.184 (0.005 to 0.415) | 0.107 (0.017 to 0.241 |
| S | 0.985 (0.804 to 1.294) | 1.303 (1.042 to 1.769) | 1.194 (1.053 to 1.406) |
| Interaction model 2† | |||
| RERI | 0.005 (−0.017 to 0.507) | 0.162 (−0.084 to 8.477) | 0.026 (−0.008 to 0.408) |
| AP | 0.005 (−0.017 to 0.531) | 0.061 (−0.067 to 0.342) | 0.018 (−0.008 to 0.134) |
| S | 0.801 (0.766 to 1.344) | 1.109 (0.759 to 1.606) | 1.064 (0.803 to 1.275) |
| Interaction model 3‡ | |||
| RERI | 0.007 (−0.061 to 1.215) | −0.033 (−0.412 to 12.725) | 0.004 (−0.016 to 0.311) |
| AP | 0.006 (−0.075 to 0.396) | 0.009 (−0.014 to 0.174) | 0.004 (−0.016 to 0.191) |
| S | 1.032 (0.596 to 1.647) | 0.972 (0.535 to 1.531) | 1.039 (0.774 to 1.285) |
Data are estimates (95% CI).
*Not adjusted for other covariates.
†Adjusted for age.
‡Adjusted for age, smoking, alcohol intake, hypertension, total cholesterol; triglycerides and 8-iso-PGF2α.
8-iso-PGF2α, 8-iso-prostaglandin F2α; AP, attributable proportion due to interaction; BMI, body mass index; RERI, relative excess risk due to interaction; S, synergy index; SF, serum ferritin.