Baseline characteristics of patients with Alzheimer's disease and their caregivers who participated in the Danish Alzheimer Intervention Study (DAISY)
| Intervention (n=163) | Control (n=167) | |
|---|---|---|
| Patients’ characteristics | ||
| Sex | ||
| Male | 76 (46.6) | 75 (44.9) |
| Female | 87 (53.4) | 92 (55.1) |
| Mean (SD) age (years) | 76.5 (7.7) | 75.9 (6.6) |
| Household status | ||
| Living alone | 54 (33.1) | 48 (28.7) |
| Living with others | 109 (66.9) | 119 (71.3) |
| Home | ||
| Rented | 66 (40.5) | 56 (33.5) |
| Owned | 97 (59.5) | 111 (66.5) |
| Education | ||
| None | 60 (36.8) | 57 (34.1) |
| <3 years | 39 (23.9) | 49 (29.3) |
| ≥3 years | 64 (39.3) | 61 (36.5) |
| Charlson comorbidity index | ||
| No comorbidity | 64 (39.3) | 73 (43.7) |
| 1 comorbidity | 75 (46.0) | 65 (38.9) |
| ≥2 comorbidities | 24 (14.7) | 29 (17.4) |
| Diagnosis | ||
| Pure Alzheimer's disease | 112 (68.7) | 127 (76.1) |
| Mixed Alzheimer's disease and vascular dementia | 44 (27.0) | 38 (22.8) |
| Lewy body dementia | 7 (4.3) | 2 (1.2) |
| Caregiver's characteristics | ||
| Sex | ||
| Male | 54 (33.1) | 56 (33.5) |
| Female | 109 (66.9) | 111 (66.5) |
| Mean (SD) age (years) | 65.5 (12.7) | 66.5 (12.7) |
| Relation | ||
| Spouse | 104 (63.8) | 111 (66.5) |
| Child or child in law | 45(27.6) | 41(24.5) |
| Other | 14 (8.6) | 15 (9.0) |
| Living with patient | ||
| Yes | 101/162 (62.4) | 112/166 (67.5) |
| No | 61/162 (37.6) | 54/166 (32.5) |
| Home | ||
| Rent | 45 (27.6) | 45 (26.9) |
| Own | 118 (72.4) | 122 (73.1) |
| Education | ||
| None | 41 (25.2) | 37/166 (22.3) |
| <3 years | 46 (28.2) | 63/166 (37.9) |
| ≥3 years | 76 (46.6) | 66 /166 (39.8) |
| Outcome measures at baseline | ||
| Primary patient outcomes | ||
| Mean (SD) MMSE | 24.0 (2.5) | 24.1 (2.7) |
| Mean (SD) Cornell Depression Scale | 5.2 (4.8) | 4.4 (4.0) |
| Mean (SD) proxy-rated EQ-VAS | 62.1 (18.4) (n=162) | 64.7 (20.4) |
| Primary caregiver outcome | ||
| Mean (SD) EQ-VAS | 79.3 (16.3) (n=162) | 81.4 (16.3) |
| Mean (SD) GDS | 4.74 (5.2) (n=162) | 4.71 (5.0) |
| Secondary patient outcome | ||
| Mean (SD) QoL-AD (proxy-rated) | 33.0 (6.1) | 34.7 (6.6) |
| Mean (SD) NPI-Q | 3.9 (3.6) | 3.9 (3.7) |
| Mean (SD) ADSC-ADL | 61.2 (11.4) | 61.8 (11.4) |
Values are numbers (percentages) of participants unless stated otherwise.
ADSC-ADL, Alzheimer's Disease Cooperative Study Activities of Daily Living Scale; EQ-VAS, European Quality of Life Visual Analogue Scale; GDS, Geriatric Depression Scale; MMSE, Mini-Mental State Examination; NPI-Q, Neuropsychiatric Inventory Questionnaire; QoL-AD, Quality of Life Scale for Alzheimer's Disease.