Second data set: clinical variables in patients with Lancefield groups A, C and G compared with patients having no growth of Lancefield groups C, G or A streptococci, with ORs (95% CI)
| Second data set | First data set | |||||
|---|---|---|---|---|---|---|
| With streptococci | No streptococci | Univariate OR | *Multivariate OR | Univariate OR | Multivariate OR | |
| Prior duration ≤3 days | 102/176 (58%) | 126/308 (41%) | 1.99 (1.37 to 2.90) | 1.67 (1.10 to 2.54) | 2.64 (1.82 to 3.82) | 1.92 (1.26 to 2.92) |
| Cervical glands | 150/188 (80%) | 245/318 (77%) | 1.18 (0.76 to 1.83) | 1.20 (0.67 to 2.16) | 4.27 (2.41 to 7.57) | 2.93 (1.55 to 5.52) |
| Severely inflamed tonsils | 38/167 (23%) | 23/294 (8%) | 3.47 (1.99 to 6.07) | 2.29 (1.23 to 4.26) | 3.62 (2.32 to 5.64) | 2.28 (1.39 to 3.74) |
| Absence of runny nose (coryza) | 149/193 (77%) | 197/323 (61%) | 1.58 (1.22 to 2.05) | 1.91 (1.21 to 3.00) | 2.17 (1.48 to 3.17) | 1.55 (0.99 to 2.41) |
| Age group ≤10 years | 12/176 (7%) | 18/308 (6%) | 1.18 (0.55 to 2.51) | 0.80 (0.35 to 1.83) | 2.54 (1.50 to 4.29) | 1.95 (1.05 to 3.62) |
| Very bad sore throat | 167/193 (87%) | 283/323 (88%) | 0.91 (0.53 to 1.54) | 1.08 (0.44 to 2.68) | 4.16 (1.75 to 9.87) | 3.31 (1.24 to 8.83) |
| Absence of cough | 127/193 (66%) | 167/324 (52%) | 1.81 (1.25 to 2.61) | 1.11 (0.70 to 1.75) | 3.83 (2.35 to 6.25) | 2.73 (1.56 to 4.76) |
| Purulent tonsils | 98/192 (51%) | 93/323 (29%) | 2.58 (1.78 to 3.74) | 1.75 (1.13 to 2.72) | 2.51 (1.75 to 3.60) | 1.06 (0.67 to 1.66) |
| Fever (last 24 h) | 137/193 (71%) | 168/324 (52%) | 2.27 (1.55 to 3.32) | 2.40 (1.52 to 3.77) | 2.80 (1.86 to 4.21) | 1.69 (1.05 to 2.71) |
| Muscle aches | 111/176 (63%) | 150/307 (49%) | 1.79 (1.22 to 2.61) | 1.31 (0.85 to 2.01) | 2.02 (1.39 to 2.94) | 2.20 (1.41 to 3.42) |
| Headache | 128/193 (66%) | 200/323 (62%) | 1.21 (0.83 to 1.76) | 1.15 (0.72 to 1.84) | 2.00 (1.36 to 2.96) | 1.41 (0.89 to 2.25) |
| Absence of cough or coryza | 110/193 (57%) | 137/323 (42%) | 1.80 (1.25 to 2.58) | 1.36 (0.89 to 2.08) | 2.66 (1.85 to 3.81) | 2.45 (1.62 to 3.68) |
*All multivariate estimates adjusted for other significant predictors in each data set.
Estimates of the univariate and multivariate analyses in the first data set are also shown for comparison.
When assessing the combined variable ‘absence of cough or coryza’, the individual items are omitted.