Association of body size with hypertension and type 2 diabetes in two population-based surveys in Shanghai, China
| Number of participants with neither disease | Type 2 diabetes only | Hypertension only | Both | ||||
|---|---|---|---|---|---|---|---|
| N | OR (95% CI) | N | OR (95% CI) | N | OR (95% CI) | ||
| BMI residuals | |||||||
| Men | |||||||
| Q1 | 1260 | 156 | 1.00 | 529 | 1.00 | 175 | 1.00 |
| Q2 | 1224 | 142 | 0.99 (0.77 to 1.27) | 583 | 1.16 (1.00 to 1.34) | 172 | 1.11 (0.87 to 1.41) |
| Q3 | 1164 | 132 | 1.09 (0.84 to 1.41) | 651 | 1.50 (1.29 to 1.74) | 171 | 1.36 (1.07 to 1.73) |
| Q4 | 1079 | 123 | 1.16 (0.88 to 1.51) | 709 | 1.85 (1.59 to 2.15) | 207 | 1.95 (1.54 to 2.47) |
| p Value for trend | 0.2472 | <0.0001 | <0.0001 | ||||
| Women | |||||||
| Q1 | 1816 | 166 | 1.00 | 600 | 1.00 | 223 | 1.00 |
| Q2 | 1866 | 148 | 1.02 (0.80 to 1.29) | 629 | 1.29 (1.12 to 1.48) | 162 | 0.96 (0.77 to 1.21) |
| Q3 | 1835 | 125 | 0.89 (0.69 to 1.15) | 687 | 1.51 (1.31 to 1.73) | 158 | 1.03 (0.82 to 1.31) |
| Q4 | 1634 | 109 | 0.94 (0.73 to 1.23) | 847 | 2.23 (1.94 to 2.57) | 215 | 1.85 (1.15 to 2.98) |
| p Value for trend | 0.4864 | <0.0001 | 0.0067 | ||||
| All participants | |||||||
| Q1 | 3048 | 330 | 1.00 | 1162 | 1.00 | 385 | 1.00 |
| Q2 | 3079 | 282 | 1.00 (0.84 to 1.19) | 1200 | 1.22 (1.11 to 1.35) | 363 | 1.03 (0.87 to 1.22) |
| Q3 | 2998 | 278 | 0.98 (0.82 to 1.18) | 1346 | 1.50 (1.36 to 1.67) | 302 | 1.18 (1.00 to 1.40) |
| Q4 | 2753 | 211 | 1.04 (0.86 to 1.26) | 1527 | 2.05 (1.85 to 2.27) | 433 | 1.88 (1.60 to 2.21) |
| p Value for trend | 0.2280 | <0.0001 | <0.0001 | ||||
| WC residuals | |||||||
| Men | |||||||
| Q1 | 1376 | 102 | 1.00 | 531 | 1.00 | 111 | 1.00 |
| Q2 | 1232 | 131 | 1.34 (1.02 to 1.78) | 601 | 1.23 (1.06 to 1.42) | 155 | 1.41 (1.07 to 1.84) |
| Q3 | 1130 | 148 | 1.39 (0.70 to 2.77) | 644 | 1.39 (1.20 to 1.62) | 197 | 1.73 (1.33 to 2.25) |
| Q4 | 989 | 172 | 1.75 (1.33 to 2.30) | 696 | 1.57 (1.35 to 1.82) | 262 | 2.25 (1.74 to 2.90) |
| p Value for trend | <0.0001 | <0.0001 | <0.0001 | ||||
| Women | |||||||
| Q1 | 2019 | 80 | 1.00 | 598 | 1.00 | 108 | 1.00 |
| Q2 | 1935 | 102 | 1.17 (0.86 to 1.59) | 651 | 1.04 (0.91 to 1.18) | 117 | 0.94 (0.71 to 1.25) |
| Q3 | 1708 | 172 | 2.04 (1.54 to 2.70) | 732 | 1.14 (0.99 to 1.30) | 194 | 1.40 (1.08 to 1.82) |
| Q4 | 1489 | 194 | 2.37 (1.78 to 3.15) | 782 | 1.13 (0.98 to 1.30) | 339 | 2.06 (1.26 to 3.38) |
| p Value for trend | <0.0001 | 0.0216 | <0.0001 | ||||
| All participants | |||||||
| Q1 | 3453 | 161 | 1.00 | 1109 | 1.00 | 203 | 1.00 |
| Q2 | 3192 | 260 | 1.26 (0.99 to 1.60) | 1211 | 1.12 (1.01 to 1.23) | 260 | 1.16 (0.82 to 1.62) |
| Q3 | 2838 | 301 | 1.66 (1.16 to 2.36) | 1373 | 1.25 (1.13 to 1.38) | 412 | 1.55 (1.29 to 1.87) |
| Q4 | 2395 | 379 | 2.03 (1.66 to 2.47) | 1542 | 1.34 (1.09 to 1.64) | 608 | 2.18 (1.83 to 2.61) |
| p Value for trend | 0.0001 | 0.0021 | <0.0001 | ||||
p Values less than 0.05 (shown in italic typeface) were considered as a test of significance based on two sides.
Missing values were excluded from the analysis.
OR: adjusted for age (continuous variable), education (no formal education, primary school, middle school, high school, colleague or above and dummy variables), per capita income (<1000, 1000–2999, 3000–5000 and >5000 RMB yuan/month, dummy variables), resident site (urban/rural area), family history of type 2 diabetes (yes/no), smoking (ever/never), alcohol drinking (ever/never), regular exercise (never/ever), phase of study (first/second survey); additionally adjusted for sex (male/female) for all participants.
BMI, body mass index; WC, waist circumference.