Association of asthma control status and therapy with risk of community-acquired Escherichia coli bloodstream infection
| Asthma characteristics | Total (n=518) | Unadjusted OR (95% CI), p Value | Adjusted OR* (95% CI), p Value |
|---|---|---|---|
| Inhaled corticosteroid therapy (ICS) | p=0.009† | p=0.079† | |
| No asthma | 465 (90%) | Referent | Referent |
| Asthma without ICS | 35 (7%) | 1.90 (0.88 to 4.09) | 1.99 (0.67 to 5.94) |
| Asthma with ICS | 18 (3%) | 7.00 (1.59 to 30.80) | 5.33 (0.90 to 31.66) |
| Asthma status‡ | p=0.005† | p=0.067† | |
| No asthma | 465 (90%) | Referent | Referent |
| Remission or inactive asthma | 17 (3%) | 1.25 (0.45 to 3.50) | 1.25 (0.25 to 6.30) |
| Active or current asthma | 36 (7%) | 4.37 (1.80 to 10.62) | 3.89 (1.23 to 12.28) |
*Adjusted variables included all factors reported in the multivariable model (see table 2) except for dichotomous asthma status.
†p Value for overall comparison.
‡Active or current asthma was defined as the presence of asthma-related events including asthma symptoms, or use of asthma medications, and outpatient/emergency department/hospitalisation for asthma within 1 year prior to index date of E coli BSI; remission of asthma was defined as the absence of asthma-related events >3 years prior to index date; inactive (not current) asthma was defined as the presence of asthma-related events within 1–3 years prior to index date.