Sensitivity analysis
| Usual care | PhysioDirect | Incremental difference (95% CI) | |||
|---|---|---|---|---|---|
| n | Mean (SD) cost | n | Mean (SD) cost | ||
| (1) Mimicking an efficient service | |||||
| Cost of physiotherapy | 432 | £76.56 (£55.34) | 840 | £72.22 (£61.55) | −£4.34 (−£11.25 to £2.57) |
| Cost of NHS services | 432 | £100.91 (£502.02) | 840 | £112.23 (476.91) | £11.32 (−£45.08 to £67.72 |
| Total cost | 432 | £177.46 (£504.49) | 840 | £184.44 (£481.83) | £6.98 (−£49.89 to £63.85) |
| Incremental cost-effectiveness ratio (ICER) | £1045 | ||||
| Median net monetary benefit (95% CI) based on bootstrapped results | |||||
| λ=£20 000 | £127 (−£74 to £319) | ||||
| λ=£30 000 | £193 (−£95 to £473) | ||||
| (2) Excluding hospital costs | |||||
| Cost of physiotherapy | 448 | £78.49 (£57.14) | 869 | £86.84 (£65.25) | £8.35 (£1.21 to £15.50) |
| Cost of NHS services excluding secondary care | 448 | £33.75 (£76.46) | 869 | £33.49 (£63.76) | −£0.25 (−£8.05 to £7.54) |
| Total cost of NHS services including physiotherapy | 448 | £112.23 (£99.621) | 869 | £120.33 (£98.85) | £8.10 (−£3.21 to £19.41) |
| Incremental cost-effectiveness ratio (ICER) | £1084 | ||||
| Median net monetary benefit (95% CI) based on bootstrapped results | |||||
| λ=£20 000 | £142 (−£41 to £324) | ||||
| λ=£30 000 | £217 (−£56 to £489) | ||||
| (3) Imputed data | |||||
| Cost of physiotherapy | 743 | £69.73 (£56.17) | 1506 | £74.01 (£63.97) | £4.28 (−£1.12 to £9.69) |
| Cost of NHS services | 743 | £131.37 (£465.49) | 1506 | £131.51 (£384.36) | £0.17 (−£36.13 to £36.48) |
| Total cost of NHS services including physiotherapy | 743 | £201.09 (£467.51) | 1506 | £205.55 (£390.04) | £4.46 (−£32.22 to £41.14) |
| Quality-adjusted life years | 743 | 0.320 (0.003) | 1506 | 0.322 (0.002) | 0.002 (−0.006 to 0.009) |
| Incremental cost-effectiveness ratio (ICER) | £2260 | ||||
| Median net monetary benefit (95% CI) based on bootstrapped results | |||||
| λ=£20 000 | £34 (−£119 to £193) | ||||
| λ=£30 000 | £52 (−£172 to £285) | ||||
| (4) Imputed data and ‘efficient’ service | |||||
| Cost of physiotherapy | 743 | £67.61 (£54.19) | 1506 | £61.41 (£59.13 | −£6.20 (−£11.26 to −£1.14) |
| Cost of NHS services | 743 | £131.37 (£465.49) | 1506 | £131.54 (384.36) | £0.17 (−£36.13 to £36.48) |
| Total cost of NHS services including physiotherapy | 743 | £198.98 (£467.48) | 1506 | £192.95 (£389.52) | −£6.02 (−£42.68 to £30.63) |
| Quality-adjusted life years | 743 | 0.320 (0.003) | 1506 | 0.322(0.002) | 0.002 (−0.006 to 0.009) |
| Incremental cost-effectiveness ratio (ICER) | −£3054 | ||||
| Median net monetary benefit (95% CI) based on bootstrapped results | |||||
| λ=£20 000 | £47 (−£113 to £202) | ||||
| λ=£30 000 | £67 (−£165 to £293) | ||||
NHS, National Health Service.