Demographics, risk factors and laboratory measurements for non-fatal myocardial infarction cases and controls from the SHEEP study in Stockholm 1992–1994
| Population controls (n=1506) | MI cases (n=1192) | |||||
|---|---|---|---|---|---|---|
| n | Per cent | n | Per cent | |||
| Sex (male) | 1013 | 67.3 | 843 | 70.7 | ||
| Family history of CHD | 398 | 26.8 | 497 | 42.6 | ||
| Physical inactivity | 533 | 35.7 | 538 | 45.6 | ||
| Hypertension | 849 | 56.4 | 609 | 51.1 | ||
| Diabetes mellitus | 120 | 8.0 | 231 | 19.4 | ||
| Job strain | 368 | 24.6 | 369 | 31.6 | ||
| Smoking status | ||||||
| Never smokers | 604 | 40.1 | 296 | 24.8 | ||
| Ex-smokers | 471 | 31.3 | 313 | 26.3 | ||
| Current smokers | 431 | 28.6 | 583 | 48.9 | ||
| n | Mean (SD) | Median (min–max) | n | Mean (SD) | Median (min–max) | |
| Age (years) | 1506 | 60.0 (7.2) | 61.0 (44.5–70.9) | 1192 | 59.3 (7.2) | 60.0 (44.5–70.9) |
| Body mass index (kg/m2) | 1460 | 25.8 (3.8) | 25.3 (16.6–45.3) | 1192 | 26.8 (4.1) | 26.4 (14.5–43.1) |
| IL-6 (ng/L) | 879 | 5.2 (19.6) | 1.1 (0–238.7) | 812 | 8.4 (30.0) | 1.4 (0–263.4) |
| TNF-α (ng/L) | 1015 | 2.2 (1.9) | 1.7 (0.3–22.8) | 808 | 2.3 (1.9) | 1.9 (0.3–26.5) |
| Fibrinogen (g/L) | 1462 | 3.5 (0.7) | 3.4 (1.5–9.1) | 1109 | 3.8 (0.9) | 3.6 (1.8–8.5) |
| PAI-1 (U/mL) | 1479 | 15.2 (13.7) | 12.0 (0–113.0) | 1124 | 20.4 (18.9) | 16.5 (0–195.0) |
| CRP (mg/L) | 1168 | 2.5 (5.5) | 1.2 (0–126.0) | 873 | 4.1 (6.7) | 2.0 (0.04–87.4) |
| LDL cholesterol, mmol/L | 1489 | 4.0 (1.0) | 3.9 (0.5–9.2) | 1150 | 4.2 (1.0) | 4.2 (1.4–8.5) |
| HDL cholesterol, mmol/L | 1495 | 1.3 (0.4) | 1.2 (0.4–2.9) | 1172 | 1.1 (0.3) | 1.0 (0.5–2.6) |
| Triglycerides, mmol/L | 1503 | 1.5 (0.9) | 1.3 (0.3–12.5) | 1188 | 2.0 (1.5) | 1.7 (0.5–19.5) |
| Insulin, µU/mL | 1175 | 10.4 (7.9) | 8.0 (3.0–75.0) | 884 | 13.8 (11.5) | 10.0 (3.0–85.0) |
CHD, coronary heart disease; CRP, C reactive protein; HDL, high-density lipoprotein; IL-6, interleukin-6; LDL, low-density lipoprotein; MI, myocardial infarction; PAI-1, plasminogen activator inhibitor-1; TNF-α, tumour necrosis factor-α.