Table 2

Allelic and genotypic frequency

ESR1
XbaIMCIa (N=204)AD (N=350)CONTROLS (N=262)
Allele
 X0.4260.4090.395
 x0.5740.5910.605
Genotype
 XX0.1570.1540.156
 Xx0.5390.5090.477
 xx0.3040.3370.366
H-W*
 p Value0.1970.3761.000
PvuII
Allele
 P0.4880.4800.462
 p0.5120.5200.538
Genotype
 PP0.2250.2090.214
 Pp0.5250.5430.496
 pp0.2500.2490.290
H-W*
 p Value0.5750.1101.000
SNP1
Allele
  A0.1910.1890.174
  G0.8090.8110.826
Genotype
 AA0.0390.0370.030
 AG0.3040.3030.286
 GG0.6570.6600.684
H-W*
 p Value0.8180.8611.000
ESR2
SNP2
Allele
 A0.4240.4190.378
 G0.5760.5810.622
Genotype
 AA0.2010.1890.133
 AG0.4460.4600.489
 GG0.3530.3510.378
H-W*
p Value0.2450.3250.591
APOE
Allele
 20.0270.0340.057
 30.7430.6650.842
 40.2300.3010.101
Genotype
 2,20.0000.0000.008
 2,30.0440.0460.092
 2,40.0100.0170.008
 3,30.5740.4340.698
 3,40.2940.4200.195
 4,40.0780.0830.000
H-W*
p Value0.2170.8140.102
Genetic profile
 XPAA(+)0.7090.7080.674
 XPAA(−)0.2910.2920.326
  • *Hardy-Weinberg probability test