Clinical manifestations of non-plaque-type cases
| Total (n=53)* | Supratentorial group (n=20) | Infratentorial group (n=28) | p Value† | |
|---|---|---|---|---|
| Pathologically confirmed cases (%) | 18 (34) | 9 (45) | 7 (25) | ns |
| Initial manifestations‡ (%) | (n=39) | (n=16) | (n=19) | |
| Unsteady gait | 12 (31) | 4 (25) | 7 (37) | ns |
| Dementia | 11 (28) | 6 (38) | 5 (26) | ns |
| Vertigo | 6 (15) | 0 (0) | 6 (32) | 0.017 |
| Behavioural abnormality | 6 (15) | 4 (25) | 2 (11) | ns |
| Ataxia | 6 (15) | 3 (19) | 1 (5) | ns |
| Diplopia | 5 (13) | 0 (0) | 4 (21) | 0.074 |
| Sensory disturbance | 2 (5) | 1 (6) | 1 (5) | ns |
| Extrapyramidal signs | 1 (3) | 1 (6) | 0 (0) | ns |
| Visual disturbance | 1 (3) | 0 (0) | 1 (5) | ns |
| Others§ | 3 (8) | 3 (19) | 0 (0) | — |
| Manifestations during clinical course (%) | ||||
| Cerebellar signs | 35/51 (69) | 10/20 (50) | 22/26 (85) | 0.014 |
| Psychiatric feature | 32/50 (64) | 11/17 (65) | 19/28 (68) | ns |
| Dementia | 51/53 (96) | 19/20 (95) | 27/28 (96) | ns |
| Visual disturbance | 21/51 (41) | 8/19 (42) | 12/27 (44) | ns |
| Myoclonus | 50/52 (96) | 20/20 (100) | 25/26 (96) | ns |
| Extrapyramidal signs | 30/51 (59) | 12/20 (60) | 17/26 (65) | ns |
| Pyramidal signs | 40/51 (78) | 18/20 (90) | 19/26 (73) | ns |
*Total includes two cases with spinal cord regions and three cases with uncertain grafting regions.
†p Value was assessed between the supratentorial group and the infratentorial group; ns, not significant.
‡Thirteen cases of the total, 5 cases of the supratentorial group and 8 cases of the infratentorial group developed more than one initial manifestation.
§Others include individual cases of hemiparesis, dysarthria and nystagmus.