Irreversible disorders with 6-month mortality estimated at greater than 50% | Incomplete outcome data |
Rapidly developing neuromuscular disease | Incomplete study procedures |
Cardiopulmonary arrest | Unable to ensure future independent mobility |
Brain injury with Glasgow Motor Score <5 | Unable to ensure future independent mobility |
Elevated intracranial pressure | Intervention contraindicated |
Rupture/leaking aortic aneurysm | Intervention contraindicated |
Acute myocardial infarction before peak troponin has been reached | Intervention contraindicated |
Absent lower extremities | Incomplete study procedures |
Unstable fractures | Intervention contraindicated |
Prolonged hospitalisation >5 days at enrolment hospital or at an outside hospital | Potential confounding factors |
Pregnancy (women 18–55 years old) | Intervention contraindicated |
Enrolment in another clinical trial | Potential confounding factors |