Table 4

Studies by age group, directionality and quality grading

Age groupDirection of findingsNumber of studies (%)Quality grading (%)
Infancy ≤1 year of age n=18No association between IQ and BF9 (50)A—3 (33.3)
B—3 (33.3)
C—3 (33.3)
Positive association between IQ and BF5 (28)A—0 (0)
B—1 (20)
C—4 (80)
Initial positive association which became negative after adjustment for confounders.2 (11)A—0 (0)
B—1 (50)
C—1 (50)
Initial positive association weakened after adjustment for confounders but remained statistically significant2 (11)A—1 (50)
B—0 (0)
C—1 (50)
Childhood 1–18 years of age n=70No association between IQ and BF14 (20)A—3 (21)
B—5 (36)
C—6 (43)
Positive association between IQ and BF26 (37)A—10 (38.5)
B—6 (23)
C—10 (38.5)
Initial positive association which became negative after adjustment for confounders.16 (23)A—6 (37.5)
B—6 (37.5)
C—4 (25)
Initial positive association weakened after adjustment for confounders but remained statistically significant14 (20)A—12 (86)
B—2 (14)
C—0 (0)
Adulthood ≥18 years of age n=5No association between IQ and BF2 (40)A—0 (0)
B—1 (50)
C—1 (50)
Positive association between IQ and BF1 (20)A—0 (0)
B—1 (100)
C—0 (0)
Initial positive association which became negative after adjustment for confounders.1 (20)A—0 (0)
B—1 (100)
C—0 (0)
Initial positive association weakened after adjustment for confounders but remained statistically significant1 (20)A—1 (100)
B—0 (0)
C—0 (0)
  • Infancy: Refs. 22 ,24 ,35–37* 38 ,51 ,54 ,60 ,64* 69 ,70* 72* 73 ,74* 78* 86* 90*

  • Childhood: Refs. 9 ,13 ,15 ,21 ,23 ,25–34 ,37* 40–43* 45–50 ,52 ,53 ,55–59 61–64* 65–68 ,70* 72* 74* 75–78* 79–82 84–86* 87–90* 91–101

  • Adulthood: Refs. 39 ,43* 44 ,71 ,83

  • *Study examined two different age groups and therefore included in several categories.

  • BF, breastfeeding.