Table 2

Adjusted mean (SE) decreases of joint space width (JSW) by soft drink intake*

Soft drinks (times/week)	Men				Women
Soft drinks (times/week)	N	ΔJSW (mm)*	p Value	p trend	N	ΔJSW (mm)*	p Value	p trend
Overall
None	202	0.31 (0.03)	Referent		485	0.32 (0.02)	Referent
≤1	439	0.39 (0.02)	0.055		537	0.33 (0.02)	0.626
2–4	140	0.34 (0.04)	0.540		145	0.36 (0.04)	0.331
≥5	107	0.60 (0.05)	<0.001	<0.001	94	0.30 (0.05)	0.751	0.756
Non-obese
None	113	0.24 (0.04)	Referent		279	0.30 (0.03)	Referent
≤1	266	0.38 (0.03)	0.010		277	0.30 (0.03)	0.946
2–4	85	0.32 (0.05)	0.236		60	0.35 (0.06)	0.395
≥5	53	0.62 (0.07)	<0.001	<0.001	32	0.30 (0.07)	0.955	0.681
Obese
None	89	0.40 (0.05)	Referent		206	0.34 (0.03)	Referent
≤1	173	0.41 (0.03)	0.993		260	0.37 (0.03)	0.471
2–4	55	0.38 (0.06)	0.749		85	0.38 (0.05)	0.518
≥5	54	0.57 (0.06)	0.032	0.064	62	0.33 (0.06)	0.900	0.829

*Adjusted for age, race, education, marital status, household income, employment, follow-up time, body mass index, knee injury and knee surgery, smoking, milk and juice intake, total energy intake, baseline Kellgren-Lawrence grade and joint space width (JSW), weight change, the changes of rim distance and beam angle.