Variables | WHI OS | RCT for diet | RCTs for HT | |||||
---|---|---|---|---|---|---|---|---|
E+P | E-alone | No HT | E+P | E-alone | No HT | E+P | E-alone | |
Sample size | 17 618 | 21 659 | 44 597 | 8907 | 11 880 | 19 968 | 16 581 | 10 719 |
Age (years) | ||||||||
≤55 | 25.6 | 19.0 | 13.4 | 27.1 | 20.6 | 14.7 | 16.6 | 16.4 |
>70 | 9.3 | 16.8 | 25.0 | 5.6 | 11.5 | 17.8 | 17.8 | 20.1 |
Race | ||||||||
Non-white | 11.3 | 15.5 | 19.8 | 10.8 | 15.5 | 22.4 | 16.0 | 24.7 |
Family income | ||||||||
<$35 000 | 23.0 | 33.4 | 42.7 | 23.4 | 33.9 | 41.9 | 45.3 | 54.5 |
>$75 000 | 29.1 | 20.0 | 14.5 | 27.4 | 18.8 | 13.7 | 12.5 | 8.1 |
Education level | ||||||||
≤HS grad | 13.2 | 20.8 | 24.8 | 13.7 | 21.6 | 23.5 | 26.1 | 32.4 |
Col grad | 54.1 | 38.4 | 38.1 | 50.7 | 35.3 | 37.0 | 34.6 | 23.7 |
P Funct >75 | 80.2 | 68.8 | 68.2 | 78.4 | 67.7 | 67.4 | 73.6 | 61.5 |
Med visit | 84.4 | 85.3 | 76.7 | 85.7 | 86.0 | 76.2 | 68.5 | 72.3 |
Smoking | ||||||||
Past | 46.0 | 42.7 | 40.1 | 44.6 | 42.0 | 40.2 | 39.2 | 38.0 |
Current | 5.1 | 5.5 | 7.0 | 5.5 | 5.6 | 6.8 | 10.3 | 10.3 |
Meno sympt | 77.3 | 70.4 | 64.8 | 70.9 | 64.3 | 59.5 | 61.9 | 60.5 |
All characteristics differed among the four datasets and among treatment groups within the observational study and RCT for diet datasets at the p<0.0001 level.
Col, college; E-alone, oestrogen alone; E+P, oestrogen plus progesterone; grad, graduate; HS, high school; HT, hormone therapy; Med visit, visit to a physician within the past year; Meno sympt, history of menopausal symptoms; OS, observational study; P Funct, physical function score from the SF-36; RCT, randomised control trial.