TEG and MEA parameters for pSS patients, SLE patients and healthy controls
| (A) TEG | |||||||
|---|---|---|---|---|---|---|---|
| TEG parameters | |||||||
| R (mins) | K (mins)* | α Angle (degrees)* | MA (mm) | LY30 (%)* | LY60 (%) | CI | |
| pSS (n=34) | 5.5±1.3 | 1.5±0.5 | 68.1±5.5 | 65.7±3.7 | 0.7±1.7 | 4.2±2.7 | 1.2±1.5 |
| SLE (n=11) | 5.0±0.8 | 1.5±0.5 | 69.0±4.4 | 64.6±4.0 | 1.2±2.2 | 4.9±2.6 | 1.6±1.1 |
| Healthy controls (n=13) | 5.3±1.2 | 1.5±0.4 | 68.8±3.2 | 66.2±5.3 | 0.7±0.8 | 3.6±1.3 | 1.4±1.7 |
| p Value (ANOVA/Kruskal-Wallis) | 0.342 | 0.703 | 0.561 | 0.637 | 0.286 | 0.462 | 0.664 |
| (B) MEA | ||||
|---|---|---|---|---|
| MEA parameters | ||||
| AA (AU) | ADP (AU) | TRAP (AU) | COL (AU) | |
| pSS (n=34) | 89.4±22.3 | 77.6±21.0 | 101.1±22.7 | 75.2±20.5 |
| SLE (n=11) | 93.5±26.5 | 71.1±21.3 | 96.3±33.6 | 77.0±24.5 |
| Healthy controls (n=13) | 85.3±33.4 | 69.4±27.4 | 88.6±35.4 | 72.7±27.5 |
| p Value (Anova/Kruskal-Wallis) | 0.752 | 0.515 | 0.419 | 0.893 |
Normally distributed values are presented as mean±SD. Non-normally distributed values (asterisk) are presented as median±IQR. Aggregate unit (AU) values (mean±SD) shown for the platelet receptor agonists AA, ADP, COL and TRAP.
AA, archidonic acid; ANOVA, analysis of variance; CI, clotting index; COL, collagen; MEA, multiple electrode aggregometry; pSS, Primary Sjögren's syndrome; SLE, systemic lupus erythematosus; TEG, thromboelastography; TRAP, thrombin receptor-activating peptide.