Changes in outcomes between review protocol and publication
| Primary outcomes | Secondary outcomes | ||
|---|---|---|---|
| Total number of outcomes included in the review (Median, IQR, range) | 3 (IQR 2, 3 and range 1, 8) | 7 (IQR 5, 9 and range 2, 13) | |
| Reviews with any discrepancy in outcomes between protocol and full review | Protocol distinguished outcomes (n=37)* | 14 (38%) | |
| Protocol did not distinguish outcomes (n=9)† | 4 (44%) | ||
| Reviews which have upgraded at least one outcome from secondary in the protocol to primary in the full review (number of outcomes; minimum per review; maximum per review) | Protocol distinguished outcomes (n=37)* | 3 (8%) (3 outcomes) | |
| Protocol did not distinguish outcomes (n=9)† | 0 | ||
| Reviews which have downgraded at least one outcome from primary in the protocol to secondary in the full review (number of outcomes; minimum per review; maximum per review) | Protocol distinguished outcomes (n=37)* | 9 (24%) (16 outcomes; min 1, max 5) | |
| Protocol did not distinguish outcomes (n=9)† | 1 (11%) (2 outcomes) | ||
| Reviews which have added a new outcome in the full review which was not included in the protocol (number of outcomes; minimum per review; maximum per review) | Protocol distinguished outcomes (n=37)* | 2 (5%) (3 outcomes) | 2 (5%) (4 outcomes; min 1, max 3) |
| Protocol did not distinguish outcomes (n=9)† | 1(11%) (1 outcome) | 2 (22%) (2 outcomes) | |
| Reviews which have excluded an outcome from the full review which was included in the protocol (number of outcomes; minimum per review; maximum per review) | Protocol distinguished outcomes (n=37)* | 2 (5%) (10 outcomes; min 1, max 9) | 3 (8%) (5 outcomes; min 1; max 2) |
| Protocol did not distinguish outcomes (n=9)† | 0 | 0 | |
*Protocol distinguished primary from secondary outcomes.
†Protocol did not distinguish primary from secondary outcomes.