Table 3

HR for specific childhood cancers according to bereavement

CancerCases (rate per 100 000 person-years)Crude HRAdjusted HR (95% CI)*
Leukaemias
 Unexposed2522 (4.06)1.0 (ref)1.0 (ref)
 All exposed360 (3.70)1.21.12 (1.00 to 1.26)
Hodgkin's lymphoma
 Unexposed123 (0.20)1.0 (ref)1.0 (ref)
 All exposed43 (0.44)1.291.17 (0.81 to 1.67)
Non-Hodgkin's lymphoma
 Unexposed441 (0.71)1.0 (ref)1.0 (ref)
 All Exposed68 (0.70)1.030.99 (0.76 to 1.29)
CNS tumours
 Unexposed2160 (3.48)1.0 (ref)1.0 (ref)
 All exposed386 (3.97)1.191.14 (1.02 to 1.28)
Wilms’ tumour†
 Unexposed564 (0.91)1.0 (ref)1.0 (ref)
 All exposed42 (0.43)0.980.93 (0.68 to 1.28)
Testicular cancer
 Unexposed50 (0.08)1.0 (ref)1.0 (ref)
 All exposed5 (0.05)1.161.08 (0.41 to 2.88)
  • *Adjusted for country, maternal characteristics at birth (maternal age and parity) and whether child was a twin.

  • †Proportional hazards assumption not met by model for this cancer subtype.