TableĀ 1

Characteristics of 22 patients with nodding syndrome

IDAge (years)Duration of symptoms in yrsSeizure based classificationMain Psychiatric morbidityOther prominent complicationsEEG seizure classification
11411Head nodding plus other seizures typesBehaviour problems
Hallucinations
Severe cognitive impairment
Burns
Lip deformity
Severe stunting, with severe wasting
Spasticity and contractures with musculoskeletal deformities
Generalised epileptiform discharges
2135Head nodding plus other seizures typesHallucinations aggressive behaviourModerate wastingGeneralised epileptiform discharges
31510Head nodding plus other seizures typesBehaviour problems
Aggression
Pychosocial disorder
Severe wasting Speech difficultiesGeneralised epileptiform discharges
4149Head nodding onlySevere cognitive impairment
Stunting
Generalised epileptiform discharges
5169Head nodding plus other seizures typesAggressive behaviour
Wandering
Hallucinations
Severe cognitive impairment
Speech difficulties
Moderate wasting
Right temporal discharges
6145Head nodding plus other seizures typesGeneralised epileptiform discharges
7147Head nodding plus other seizures typesSevere cognitive impairment
Lip deformity
Severe wasting
Generalised epileptiform discharges
81810Head nodding plus other seizures typesAggressive behaviour
Hallucinations
Severe cognitive impairment
Speech difficulties
Generalised epileptiform discharges
9188Head nodding plus other seizures typesPsychotic symptoms
Behavioural problems
Severe cognitive impairment
Lip deformity
Speech difficulties
Severe wasting
Left temporal discharges
101611Head nodding plus other seizures typesModerate wasting
Burns
Marked lip deformity
Generalised epileptiform discharges
11159Head nodding plus other seizures typesDepressionHearing impairment
Stunting
Burns
Musculoskeletal
Deformities
Severe cognitive impairment
Severe wasting
Generalised epileptiform discharges
12138Head nodding plus other seizures typesHallucinationsGeneralised epileptiform discharges
13133Head nodding plus other seizures typesModerate wastingGeneralised epileptiform discharges
14149Head nodding plus other seizures typesHallucinationsGeneralised epileptiform discharges
15128Head nodding plus other seizures typesSevere wasting Stunting
Kyphosis, pectus deformity
Generalised skin changes
Generalised epileptiform discharges
16122Head nodding onlyStunting
Severe wasting
Generalised epileptiform discharges
17148Head nodding plus other seizures typesPost-ictal aggression
Wandering
Severe cognitive impairment
Stunting
Lip deformity
Ataxia
Speech difficulties
Spasticity and contractures with musculoskeletal deformities
Moderate wasting
Generalised epileptiform discharges
18186Head nodding plus other seizures typesModerate wastingGeneralised epileptiform discharges
19124Head nodding onlyModerate wasting StuntingGeneralised epileptiform discharges
20159Head nodding onlyStuntingGeneralised epileptiform discharges
21159Head nodding plus other seizures typesSevere cognitive impairment
Lip deformity
Speech difficulties
Stunting
Moderate wasting
Spasticity with contractures and severe musculoskeletal deformity, wasting/dystrophy
Generalised epileptiform discharges
22159Head nodding plus other seizures typesBehavioural problems
Aggression
Severe cognitive impairment
Stunting
Burns
Episodes of disorientation
Speech difficulties
Generalised epileptiform discharges