Patients N | Events N (%) | Events/1000 person-years | HR* (95% CI) | p Value | |
---|---|---|---|---|---|
Total haemorrhages, fatal/non-fatal | |||||
All | 18646 | 157 (0.8) | 2.4 | 1.41 (0.99 to 1.99) | 0.05 |
Women | 8341 | 71 (0.9) | 2.4 | 1.32 (0.79 to 2.21) | 0.3 |
Men | 10305 | 86 (0.8) | 2.3 | 1.53 (0.95 to 2.45) | 0.08 |
Cerebral haemorrhage, fatal/non-fatal | |||||
All | 18646 | 59 (0.3) | 0.9 | 1.26 (0.70 to 2.25) | 0.4 |
Women | 8341 | 23 (0.3) | 0.8 | 1.42 (0.57 to 3.58) | 0.6 |
Men | 10305 | 36 (0.3) | 1.0 | 1.13 (0.54 to 2.38) | 0.7 |
Cerebral haemorrhage, fatal | |||||
All | 18646 | 14 (0.1) | 0.2 | 1.60 (0.51 to 6.05) | 0.4 |
Women | 8341 | 3 (0.04) | 0.1 | 1.26 (0.11 to 14.3) | 0.9 |
Men | 10305 | 11 (0.1) | 0.3 | 1.68 (0.46 to 6.15) | 0.4 |
Ventricular haemorrhage, fatal/non-fatal | |||||
All | 18646 | 79 (0.4) | 1.2 | 1.27 (0.77 to 2.09) | 0.4 |
Women | 8341 | 40 (0.5) | 1.3 | 1.05 (0.52 to 2.13) | 0.9 |
Men | 10305 | 39 (0.4) | 1.1 | 1.69 (0.83 to 3.42) | 0.1 |
Other haemorrhages, fatal/non-fatal | |||||
All | 18646 | 20 (0.1) | 0.3 | 2.49 (1.00 to 6.20) | 0.05 |
Women | 8341 | 8 (0.1) | 0.3 | 2.99 (0.68 to 13.2) | 0.1 |
Men | 10305 | 12 (0.1) | 0.3 | 2.37 (0.73 to 7.71) | 0.2 |
Ventricular ulcer | |||||
All | 18646 | 93 (0.5) | 1.4 | 1.64 (1.06 to 2.53) | 0.02 |
Women | 8341 | 41 (0.5) | 1.4 | 2.32 (1.24 to 4.36) | 0.009 |
Men | 10305 | 52 (0.5) | 1.4 | 1.23 (0.67 to 2.26) | 0.4 |
Other haemorrhages: respiratory or unspecified.
*Adjusted by stratification with deciles of a propensity score including the covariates age, sex, diabetes duration, previous hospitalisation, type of hypoglycaemic treatment, glycated haemoglobin (HbA1c), smoking, body mass index, systolic blood pressure, ratio total-to-high-density lipoprotein cholesterol, albuminuria >20 µg/min, antihypertensive drugs, statins, other lipid lowering drugs, oestrogen and multidose dispensation. Sex (when applicable) and HbA1c were also added as covariates.