Patients N | Events N (%) | Events/1000 person-years | HR*(95% CI) | p Value | |
---|---|---|---|---|---|
Non-fatal/fatal CVD | |||||
5-year CVD risk <15% | 15296 | 593 (3.9) | 10.8 | 1.07 (0.88 to 1.30) | 0.5 |
5-year CVD risk >15% | 3350 | 410 (12.2) | 34.9 | 1.09 (0.88 to 1.35) | 0.4 |
Fatal CVD | |||||
5-year CVD risk <15% | 15296 | 89 (0.6) | 1.6 | 0.83 (0.51 to 1.36) | 0.5 |
5-year CVD risk >15% | 3350 | 116 (3.5) | 9.9 | 0.86 (0.57 to 1.28) | 0.5 |
Non-fatal/fatal CHD | |||||
5-year CVD risk <15% | 15296 | 409 (2.7) | 7.5 | 1.21 (0.96 to 1.51) | 0.1 |
5-year CVD risk >15% | 3350 | 289 (8.6) | 25.2 | 1.18 (0.92 to 1.51) | 0.2 |
Fatal CHD | |||||
5-year CVD risk <15% | 15296 | 74 (0.5) | 1.3 | 0.73 (0.42 to 1.28) | 0.3 |
5-year CVD risk >15% | 3350 | 102 (3.0) | 8.7 | 0.85 (0.55 to 1.30) | 0.5 |
Non-fatal/fatal stroke | |||||
5-year CVD risk <15% | 15296 | 200 (1.3) | 3.6 | 0.83 (0.59 to 1.17) | 0.3 |
5-year CVD risk >15% | 3350 | 138 (4.1) | 11.8 | 1.03 (0.71 to 1.50) | 0.9 |
Fatal stroke | |||||
5-year CVD risk <15% | 15296 | 15 (0.1) | 0.3 | 1.45 (0.49 to 4.31) | 0.5 |
5-year CVD risk >15% | 3350 | 18 (0.5) | 1.5 | 1.09 (0.40 to 2.95) | 0.8 |
Total mortality | |||||
5-year CVD risk <15% | 15296 | 370 (2.4) | 6.7 | 0.94 (0.74 to 1.20) | 0.6 |
5-year CVD risk >15% | 3350 | 285 (8.5) | 24.3 | 0.88 (0.68 to 1.14) | 0.3 |
*Adjusted by stratification with deciles of a propensity score including the covariates age, sex, diabetes duration, previous hospitalisation, type of hypoglycaemic treatment, HbA1c, smoking, BMI, systolic blood pressure, ratio total-to-HDL cholesterol, albuminuria >20 µg/min, antihypertensive drugs, statins, other lipid lowering drugs, oestrogen and multidose dispensation. Sex and HbA1c were also added as covariates.
BMI, body mass index; CHD, coronary heart disease; CVD, cardiovascular disease; HbA1c, glycated haemoglobin; HDL, high-density lipoprotein.