Characteristics of patients exhibiting criteria A versus B
| Criterion A* (N=27) | Criterion B* (N=20) | p Value | |
|---|---|---|---|
| Demographic variable | |||
| Male (%) | 52 | 55 | 0.83 |
| Mean age, years (SD) | 60 (15) | 69 (11) | 0.07 |
| Statin use at the event (%) | 1.00 | ||
| Atorvastatin | 37 | 35 | |
| Fluvastatin | 4 | 0 | |
| Pitavastatin | 4 | 10 | |
| Pravastatin | 11 | 15 | |
| Rosuvastatin | 37 | 35 | |
| Simvastatin | 7 | 5 | |
| Mean interval after initiating Statin, month (SD) | 18 (13) | 19 (20) | 0.98 |
| Laboratory information | |||
| SCr >1×ULN | 56% (9/16) | 58% (11/19) | 0.92 |
| BUN >1×ULN | 44% (7/16) | 50% (10/20) | 0.71 |
| APT >1×ULN | 56% (9/16) | 80% (16/20) | 0.12 |
| ALT >1×ULN | 38% (6/16) | 65% (13/20) | 0.10 |
*Criterion A is defined by diagnosis of ‘myositis’ or ‘rhabdomyolysis’ and criterion B is defined by creatine kinase (CK) concentration >10× times the upper limit of the normal range. Four cases met both criteria A and B.
ALT, alanine transaminase; APT, aspartate transaminase; BUN, blood urea nitrogen; SCr, serum creatinine; ULN, upper limit of the normal range.