Characteristics of studies included in our preferred meta-analysis
| Source | Inclusion criteria | Exclusion criteria | Antibiotic used | Oxford Quality Scale scores | |||
|---|---|---|---|---|---|---|---|
| Randomisation | Double-blinding | Withdrawals | Total | ||||
| Wax et al8 | Single fetus ≥37 weeks of gestation | Penicillin or cephalosporin allergy, antibiotic use within 2 weeks of delivery, temperature ≥37.8°C, administration of B streptococcal orsubacute bacterial endocarditis prophylaxis, insulin-dependent diabetes mellitus, human immunodeficiency virus infection, chronic glucocorticoid use, multiple gestation | Cefazolin 1 g | 2 | 2 | 1 | 5 |
| Thigpen et al9 | Acute chorioamnionitis, allergy to penicillin or cephalosporins, caesarean section without labour, systemic antibiotics within past 2 weeks | Cefazolin 2 g | 2 | 2 | 1 | 5 | |
| Sullivan et al10 | >24 weeks gestational age | Cephalosporin allergy, age <18 years, antibiotic exposure within 1 week of delivery, emergency caesarean section | Cefazolin 1 g | 2 | 2 | 1 | 5 |
| Nokiani et al11 | Normal healthy women, afebrile, amniotic membrane intact or ruptured for not more than 18 h, first caesarean section | Confirmed systemic disease (diabetes mellitus, hypertension, immune compromised diseases, coagulation disorders, heart or renal failure) | Cefazolin 2 g | 1 | 1 | 0 | 2 |
| Witt et al6 | Gestational age ≥37 weeks, reassuring fetal heart traces; rupture of membranes and labor contractions were allowed | Fever >38°C, cephalosporin allergy, age <18 years, antibiotic exposure within 1 week before delivery | Cefazolin 2 g | 2 | 2 | 1 | 5 |