Predictors of death within 3 years of study initiation, assessed with both univariate and multivariate analyses
| Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|
| Variables | HR | 95% CI | X2 | p Value | HR | 95% CI | p Value |
| Age (years) | 1.06 | 1.03 to 1.09 | 16.0 | p<0.001 | 1.06 | 1.02 to 1.09 | 0.002 |
| ALP (µkat/l) | 1.09 | 1.02 to 1.16 | 8.05 | p=0.010 | 1.08 | 0.98 to 1.18 | 0.13 |
| UREA (mmol/l) | 1.06 | 1.03 to 1.10 | 14.2 | p<0.001 | 0.98 | 0.89 to 1.07 | 0.63 |
| Creatine (mol/l) | 1.003 | 1.001 to 1.005 | 6.87 | p=0.011 | 1.00 | 0.99 to 1.005 | 0.55 |
| Orosomucoid (g/l) | 2.15 | 1.12 to 4.15 | 5.26 | p=0.022 | 1.24 | 0.57 to 2.68 | 0.59 |
| NTproBNP (ng/l) | 1.00006 | 1.00004 to 1.00009 | 28.5 | p<0.001 | 1.000017 | 0.99997 to 1.00006 | 0.47 |
| TnT (µg/l) | 2.94 | 1.06 to 8.15 | 4.84 | p=0.038 | 147.0 | 11.2 to 1929.8 | < 0.001 |
| CK-MB (ng/ml) | 1.11 | 1.002 to 1.23 | 4.05 | p=0.045 | 0.93 | 0.76 to 1.13 | 0.45 |
| CysC (mg/l) | 2.56 | 1.70 to 3.85 | 20.4 | p<0.001 | 6.57 | 1.80 to 24.0 | 0.004 |
ALP, alkaline phosphatase; ASAT, aspartate transaminase; CK-MB, creatine kinase–myocardial band isoenzyme; COPD, chronic obstructive pulmonary disease; CRP, C reactive protein; CysC, cystatin C; hypertension, systolic blood pressure>140 and/or diastolic blood pressure>90; diabetes, on diabetic medication; IgG, immunoglobulin G; IgM, immunoglobulin M; LDL, low-density lipoprotein; NTproBNP, N-terminal pro-B-type natriuretic peptide; stroke, ischaemic or haemorraghic stroke in the past; TnT, troponin T; TSH, thyroid stimulating hormone.
X2=51.0 for the multivariate model.