Signs and symptoms | Male:female | Moderate/severe soft tissue destruction (%) | Osteolysis (%) | Percentage of ALVAL or mixed response (percentage of lymphoid neogenesis) | Median (range) (blood Co) (µg/l) |
---|---|---|---|---|---|
Group 1 (n=21) | |||||
Increasing pain and moderate large fluid effusion | 5:16 | 47 | 81 | 71 (43) | 17.8 (4.60–109.7) |
Group 2 (n=11) | |||||
Pain with small fluid effusion | 5:6 | 18 | 55 | 18 (0) | 23.3 (1.37–147) |
Group 3 (n=4) | |||||
Acute pain with femoral collapse | 3:1 | 0 | 100 | 25 (0) | 49.8 (12.0–271.0) |
Group 4 (n=4) | |||||
Minor discomfort and grossly elevated ions with mass (n=1) grinding sensation (n=1), gross femoral neck thinning (n=1), squeaking (n=1) | 3:1 | 50 | 75 | 50 (50) | 81.8 (11.6–164) |
Avascular necrosis (non ARMD) (n=1) | 1:0 | 0 | 0 | Histiocytic | 1.90 |
ARMD, adverse reaction to metal debris; ALVAL, aseptic lymphocyte dominated vasculitis associated lesion; Co, cobalt.