HR (95% CI) for retirement in relation to socioeconomic and clinical factors among 4343 patients aged 18–63 diagnosed with colorectal cancer in the years 2001 to 2009, and part of the work force at the time of follow-up
| Mutually adjusted and controlled for confounders† | HR for transition from sickness absence—retirement (number of events: 569) | HR for transition from work/unemployed -> retirement (number of events: 109) |
|---|---|---|
| Status | ||
| Working | – | 1 |
| Unemployed | 5.89 (3.46 to 10.03)** | |
| Education | ||
| Primary school | 1 | 1 |
| Vocational and short-term education | 1.13 (0.85 to 1.51) | 1.29 (0.65 to 2.69) |
| Medium-term and long-term education | 1.06 (0.81 to 1.41) | 1.24 (0.64 to 2.53) |
| Disposal income‡ | ||
| Lowest quartile | 1 | 1 |
| Second lowest quartile | 0.95 (0.76 to 1.19) | 0.49 (0.27 to 0.85)* |
| Second highest quartile | 0.77 (0.60 to 0.98)* | 0.47 (0.25 to 0.83)* |
| Highest quartile | 0.79 (0.60 to 1.04) | 0.29 (0.14 to 0.57)* |
| Job type | ||
| Management and knowledge work | 0.59 (0.42 to 0.82)* | 0.93 (0.85 to 1.03) |
| Office and sale (non-manual) | 0.72 (0.580.89)* | 0.96 (0.86 to 1.06) |
| Manual | 1 | 1 |
| Other | 1.05 (0.06 to 4.85) | 0.38 (0.12 to 1.37) |
| Previous episodes of work | 0.98 (0.95 to 1.00) | 0.93 (0.85 to 1.03) |
| Previous episodes of sickness absence | 1.00 (0.97 to 1.02) | 0.96 (0.86 to 1.06) |
| Previous episodes of unemployment | 1.03 (1.00 to 1.05)* | 1.02 (0.94 to 1.11) |
| Type of cancer | ||
| Colonic | 1 | 1 |
| Rectal | 1.32 (1.04 to 1.67)* | 1.33 (0.75 to 2.34) |
| Stage | ||
| I | 1 | 1 |
| II | 0.85 (0.46 to 1.46) | 1.70 (0.49 to 4.51) |
| III | 1.13 (0.89 to 1.44) | 1.91 (1.15 to 3.21)* |
| IV | 1.58 (1.04 to 2.42)* | 2.30 (0.88 to 6.14) |
| Unknown | 1.01 (0.68 to 1.50) | 1.72 (0.82 to 3.59) |
| Comorbidity | ||
| No | 1 | 1 |
| Yes | 1.03 (0.85 to 1.24) | 1.17 (0.76 to 1.77) |
| ASA | ||
| I | 1 | 1 |
| II | 1.31 (1.08 to 1.58)* | 1.56 (1.00 to 2.44)* |
| III | 2.16 (1.49 to 3.06)* | 2.57 (1.03 to 5.75)* |
| Unknown | 1.29 (0.76 to 2.09) | 1.64 (0.50 to 4.24) |
| Curative operation | ||
| Yes | 1 | 1 |
| No | 1.30 (0.89 to 1.86) | 1.80 (0.77 to 3.84) |
| Unknown | 1.41 (0.75 to 2.51) | 1.05 (0.19 to 4.01) |
| Type of operation | ||
| Rectal resection | 1 | 1 |
| Colonic resection | 1.42 (1.11 to 1.81)* | 1.36 (0.74 to 2.51) |
| Explorative laparotomy or formation of an ostomy | 1.06 (0.78 to 1.43) | 1.23 (0.55 to 2.32) |
| Local procedures | 1.01 (0.53 to 1.84) | 0.39 (0.08 to 1.26) |
| Unknown | 1.45 (0.93 to 2.18) | 0.84 (0.16 to 3.13) |
| Postoperative complications | ||
| No | 1 | 1 |
| Yes | 1.23 (1.00 to 1.51)* | 0.86 (0.47 to 1.46) |
*Significant at 0.05 level.**Significant at <0.0001 level.
†Confounders: gender, age at time of diagnosis, country of birth, marital status and year of operation.‡Depending on the year, the highest disposal income ranged from 175 500 DKr in 2001 to 299 717 DKr in 2009.
ASA, the American Society of Anesthesiologists; DKr, Danish krone.