Baseline characteristics in 145 346 patients with a first event of acute myocardial infarction (AMI) or unstable angina pectoris (UAP) and OR for presenting with AMI (1996–2009)
| N (%) | UAP 47386 (33) | AMI 97960 (67) | Age-adjusted and sex-adjusted OR | p Value | Multiple adjusted OR (99% CI)* | p Value |
|---|---|---|---|---|---|---|
| Age, mean years | 68.2 | 69.7 | 1.01 (1.01 to 1.01) | <0.001 | 1.03 (1.03 to 1.03) | <0.001 |
| Women | 21 095 (44.5) | 37 016 (37.8) | 0.79 (0.68 to 0.72) | <0.001 | 0.69 (0.66 to 0.73) | <0.001 |
| Never smoker | 22 135 (52.9) | 42 885 (48.0) | 1.00 (ref) | <0.001 | 1.00 (ref) | <0.001 |
| Ex-smoker | 12 434 (29.7) | 23 920 (26.8) | 0.98 (0.95 to 1.00) | ns | 0.97 (0.92 to 1.03) | <0.001 |
| Current smoker | 7281 (17.4) | 22 545 (25.2) | 1.87 (1.80 to 1.93) | <0.001 | 1.66 (1.56 to 1.78) | <0.001 |
| Hypertension | 18 116 (40.7) | 35 710 (37.2) | 0.95 (0.94 to 0.97) | <0.001 | 1.07 (1.02 to 1.12) | <0.001 |
| Heart failure | 4708 (9.9) | 5806 (5.9) | 0.51 (0.49 to 0.53) | <0.001 | 0.57 (0.52 to 0.62) | <0.001 |
| Diabetes | 7075 (14.9) | 16 274 (16.6) | 1.13 (1.10 to 1.17) | <0.001 | 1.44 (1.34 to 1.54) | <0.001 |
| Peripheral arterial disease | 1734 (3.7) | 3797 (3.9) | 1.00 (0.92 to 1.08) | ns | 1.28 (1.13 to 1.45) | <0.001 |
| Aspirin | 20 711 (45.9) | 25 293 (26.3) | 0.38 (0.37 to 0.39) | <0.001 | 0.59 (0.56 to 0.63) | <0.001 |
| β-Blockers | 19 571 (43.4) | 25 743 (26.8) | 0.47 (0.46 to 0.48) | <0.001 | 0.72 (0.68 to 0.76) | <0.001 |
| ACE inhibitors | 7470 (16.6) | 12 680 (13.2) | 0.74 (0.72 to 0.76) | <0.001 | 0.94 (0.88 to 1.02) | ns |
| Long-acting nitrates | 12 253 (27.2) | 8140 (8.5) | 0.22 (0.21 to 0.23) | <0.001 | 0.34 (0.32 to 0.37) | <0.001 |
| Statins | 9818 (21.8) | 10 258 (10.7) | 0.44 (0.42 to 0.45) | <0.001 | 0.63 (0.58 to 0.68) | <0.001 |
*Adjusted for age, smoking, hypertension, heart failure, diabetes, peripheral arterial disease, aspirin, β-blockers, ACE inhibitors, long-acting nitrates and statins.