Regression coefficients and development of updated ADO index
| Variable | Regression coefficients βs per unit increase | Categories | Reference values Wij (mid point) | βs*(Wij-*W1reference) | Risk score=βs*(Wij-*W1reference)/B† |
|---|---|---|---|---|---|
| FEV1 (% predicted) | −0.0288 (SE 0.0023, p<0.0001) | ≥81 | 87.0 (W2reference) | 0 | |
| ≥65–80 | 72.5 | 0.418 | 1 | ||
| ≥50–64 | 57.0 | 0.864 | 2 | ||
| ≥36–49 | 42.5 | 1.282 | 3 | ||
| ≤35 | 25.0 | 1.786 | 4 | ||
| Dyspnoea (mMRC, 0–4) | 0.2585 (SE 0.0406, p<0.0001) | 0 | 0 (W3reference) | 0 | |
| 1 | 1 | 0.259 | 1 | ||
| 2 | 2 | 0.517 | 1 | ||
| 3 | 3 | 0.776 | 2 | ||
| 4 | 4 | 1.034 | 3 | ||
| Age (years) | 0.0703 (SE 0.0048, p<0.0001) | 40–49 | 44.5 (W4reference) | 0 | |
| 50–59 | 54.5 | 0.703 | 2 | ||
| 60–69 | 64.5 | 1.406 | 4 | ||
| 70–79 | 74.5 | 2.109 | 5 | ||
| ≥80 | 84.5 | 2.812 | 7 |
†1 Point is assigned per 15% in FEV1=coefficient of 0.40. Points rounded to the next integer. Constant of regression equation=−5.640.
MRC, Medical Research Council.