Table 4

Associations between extensive drug changes, ≥5 in hospital and ≥4 after discharge, and various variables

Dependent variable: ≥5 changes in drug regimen versus fever drug changes during hospital stay
	Univariate			Multivariate
	p Values	OR	95% CI	–p Values	OR	95% CI
Gender (female=1, male=0)	0.02	2.60	1.14 to 5.91	0.04	2.59	1.04 to 6.45
Age	0.95	1.00	0.97 to 1.03	ns
Length of stay	0.01	1.06	1.02 to 1.11	0.01	1.08	1.02 to 1.13
No.of drugs* at admission	0.51	1.04	0.93 to 1.16	ns
Reduced renal function (CrCl<; 50 ml/min) (no=1, yes=0)	0.08	2.09	0.91 to 4.78	ns
Heart failure (yes=1, no=0)	0.99	0.99	0.35 to 2.81	ns
Dependent variable: ≥4 changes in drug regimen vs fever drug changes at the follow-up visit at GP
Gender (female=1, male=0)	0.66	1.19	0.55 to 2.60	ns
Age	0.89	1.00	0.97 to 1.04	ns
Length of stay	0.27	1.02	0.99 to 1.05	ns
Number of drugs* at admission	0.00	1.34	1.16 to 1.54	ns
No.of drugs* at discharge	0.00	1.41	1.21 to 1.64	0.02	1.29	1.04 to 1.59
No.of drug changes at hospital	0.04	1.18	1.01 to 1.38	ns
Discharge note received within the time of follow-up (1=no, 1=yes)	0.45	1.51	0.52 to 4.41	ns
Reduced renal function (CrCl<; 50 ml/min) (no=1, yes=0)	0.64	1.22	0.54 to 2.75	ns
Heart failure (yes=1, no=0)	0.78	0.86	0.30 to 2.43	ns