Baseline clinical, echocardiographic and MR characteristics
| Clinical | |
|---|---|
| Number of patients, n (%) | 76 |
| Males, n (%) | 51 (67) |
| Age (years) | 48 (41–61) |
| Family history of HCM, n (%) | 34 (45) |
| Family history of SD, n (%) | 10 (13) |
| NYHA functional class I, n (%) | 61 (80) |
| NYHA functional class II, n (%) | 14 (18) |
| Unexplained syncope, n (%) | 12 (16) |
| NSVT on Holter monitor, n (%) | 21 (28) |
| Echocardiography | |
| LV gradient ≥30 mm Hg at rest, n (%) | 20 (26) |
| Maximum WT (mm) | 20 (17–23) |
| Maximum WT ≥30 mm, n (%) | 3 (4) |
| Left atrium diameter (mm) | 43 (39–48) |
| MRI | |
| LV mass (g/m²) | 155 (124–196) |
| LV mass/end-diastolic volume (g/ml) | 1.09 (0.92–1.46) |
| LGE % of LV mass (%) | 2.4 (0–6) |
Continuous variables are expressed as median values (IQR).
HCM, hypertrophic cardiomyopathy; LGE, late gadolinium enhancement; LV, left ventricle; NSVT, non-sustained ventricular tachycardia; NYHA, New York Heart Association; SD, sudden death; WT, wall thickness.