Association of IHF1α IHC with clinicopathological variables
| Negative | Positive | p Value | |
|---|---|---|---|
| Variables | (n=66) | (n=213) | |
| Age (median) | 65 | 65 | 0.3571* |
| Myometrial invasion (median) | 40 | 25 | 0.0646** |
| Stage | |||
| I | 39 (59.09) | 142 (66.67) | 0.6376 |
| II | 10 (15.15) | 25 (11.74) | |
| III | 11 (16.67) | 32 (15.02) | |
| IV | 6 (9.09) | 14 (6.57) | |
| Tumour size (cm) | |||
| ≤2 | 15 (22.73) | 47 (22.07) | 1 |
| >2 | 51 (77.27) | 166 (77.93) | |
| LVI | |||
| No | 46 (69.7) | 156 (73.24) | 0.6367 |
| Yes | 20 (30.3) | 57 (26.76) | |
| Grade_FIGO | |||
| 1 | 22 (33.33) | 97 (45.54) | 0.0231 |
| 2 | 9 (13.64) | 44 (20.66) | |
| 3 | 35 (53.03) | 72 (33.8) | |
| Grade_nuclear | |||
| 1 | 19 (28.79) | 74 (34.74) | 0.0368 |
| 2 | 12 (18.18) | 63 (29.58) | |
| 3 | 35 (53.03) | 76 (35.68) | |
| Lymph node status | |||
| Positive | 14 (26.92) | 36 (27.07) | 1 |
| Negative | 38 (73.08) | 97 (72.93) | |
| Subtype | |||
| CCC+Serous | 26 (39.39) | 51 (23.94) | 0.018 |
| Endometrioid | 40 (60.61) | 162 (76.06) | |
| Recurrence | |||
| No | 48 (81.36) | 167 (82.27) | 0.849 |
| Yes | 11 (18.64) | 36 (17.73) | |
| Status | |||
| ANED | 40 (60.61) | 148 (69.48) | 0.1805 |
| Others | 26 (39.39) | 65 (30.52) | |
*p Value calculated by logistic linear regression.
**p Value calculated by Fisher's exact test.
ANED, alive with no evidence of disease; FIGO, International Federation of Gynecology and Obstetrics; HIF1α, hypoxia-inducible factor-1α; IHC, immunohistochemical; LVI, lymphovascular invasion.