Distribution of ICAM-1 rs5498 genotype and allele frequencies in DR+ and DR− groups
| Genotype | Groups | p Values | |||
|---|---|---|---|---|---|
| DR− controls (n=157) | DR+ case (n=199) | Dominant AA+AG=GG | Recessive AA=AG+GG | ||
| GG | 44 (28.0) | 47 (23.6) | 0.344 | 0.4 | 0.01* |
| AG | 84 (53.5) | 92 (46.2) | 0.173 | ||
| AA | 29 (18.5) | 60 (30.2) | 0.012* | ||
| Alleles | |||||
| G | 172 (54.8) | 186 (46.7) | |||
| A | 142 (45.2) | 212 (53.3) | 0.033* | ||
*p<0.05—significant p value.
DR+, T2D subjects with retinopathy; DR−, T2D subjects without retinopathy; ICAM-1, intercellular adhesion molecule-1.