Mixed treatment comparisons (MTC) and direct evidence for the oral and intravenous administered medication. Upper right quadrants indicate the number of direct comparisons available, the direct ORs and 95% CIs, lower left quadrants indicate the MTC median OR and credible regions. Beneath the table is the estimated most likely treatment to stop children from vomiting: intravenous administered medication
| OR of the direct evidence | ||||
| Placebo | Dexamethasone | Metoclopramide | Ondansetron | |
| Median OR from the MTC | ||||
| Placebo | – | 0.83 (0.36 to 1.94) | 2.50 (0.36 to 17.32) | 4.54 (2.45, 8.44)*** |
| Dexamethasone | 0.98 (0.08 to 9.58) | – | No data available | 2.55 (1.07 to 6.08)** |
| Metoclopramide | 2.95 (0.41 to 24.27) | 3.01 (0.16 to 81.22) | – | 1.78 (0.91 to 3.45)* |
| Ondansetron | 5.44 (1.43 to 23.83)*** | 5.55 (0.45 to 101.7) | 1.85 (0.30 to 11.76) | – |
*p<0.1; **p<0.05; ***p<0.01.
Estimated best treatment option: ondansetron 75%, metoclopramide 20%, dexamethasone 6% and placebo 0%.