Prevalence and odds of significant sleep disturbance (ie, Medical Outcomes Study SPI >25) at postintervention
| Prevalence | Model 1 | Model 2 | Model 3 | Model 4 | |
| n (%) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Control | 41 (45) | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) | 1.00 (Referent) |
| 4 KKW | 46 (31) | 0.37 (0.19 to 0.73) | 0.37 (0.19 to 0.73) | 0.34 (0.19 to 0.73) | 0.37 (0.19 to 0.73) |
| 8 KKW | 33 (33) | 0.36 (0.17 to 0.77) | 0.36 (0.17 to 0.77) | 0.32 (0.17 to 0.77) | 0.36 (0.17 to 0.77) |
| 12 KKW | 31 (33) | 0.34 (0.16 to 0.72) | 0.34 (0.16 to 0.72) | 0.28 (0.16 to 0.72) | 0.34 (0.16 to 0.72) |
| Linear trend P | 0.01 | 0.01 | 0.006 | 0.02 | |
| Weight change | – | 1.00 (0.93 to 1.08) | – | – | |
| VO2peak change | – | – | 1.10 (0.95 to 1.26) | – | |
| rMSSD change | – | – | – | 1.01 (0.98 to 1.04) |
Model 1 adjusted for age, BMI, sleep medication use, hormone replacement therapy use and baseline sleep quality (SPI ≤25, SPI >25); model 2 adjusted for change in body weight in addition to variables included in model 1; model 3 adjusted for change in VO2peak in addition to variables included in model 1; model 4 adjusted for change in rMSSD in addition to variables included in model 1.
KKW, kilocalories of energy expenditure per kilogram of body weight per week; rMSSD, square root of the mean of the sum of the squares of differences between adjacent R–R intervals; SPI, Sleep Problems Index; VO2peak, peak rate of oxygen consumption.