The relationships between demographic/clinical variables and the propensity for receipt of vasoactive therapy
| All patients, OR (95% CI) | Treated patients, OR (95% CI) | Fluid-resuscitated patients, OR (95% CI) | |
| Age (year) | 0.99* (0.99 to 1.00) | 0.99 (0.98 to 1.01) | 0.99 (0.98 to 1.01) |
| Gender (male) | 1.55* (1.25 to 1.92) | 1.21 (0.87 to 1.67) | 1.34 (0.83 to 2.18) |
| SAPS | 1.12* (1.09 to 1.14) | 1.09* (1.06 to 1.13) | 1.12* (1.07 to 1.17) |
| Elixhauser | 1.08* (1.01 to 1.17) | 1.30* (1.03 to 1.64) | NA |
| Mean MAP prior to HE (mm Hg) | 1.01 (0.99 to 1.02) | 1.01 (0.99 to 1.03) | 1.00 (0.98 to 1.03) |
| Urine output prior to HE >200 ml | 0.71* (0.57 to 0.88) | 0.85 (0.61 to 1.18) | 0.98 (0.60 to 1.59) |
| Creatinine prior to HE (mg/dl) | 1.01 (0.92 to 1.11) | 1.28* (1.07 to 1.52) | 1.29* (1.02 to 1.64) |
| Total volume of fluids given prior to HE (L) | 1.01 (0.97 to 1.05) | 1.01 (0.96 to 1.07) | 0.97 (0.89 to 1.05) |
| Service type | |||
| MICU† | 1 | 1 | 1 |
| SICU | 0.74 (0.53 to 1.03) | 0.95 (0.60 to 1.50) | 1.28 (0.64 to 2.56) |
| CCU | 1.37 (0.97 to 1.94) | 1.68 (1.00 to 2.84) | 1.41 (0.59 to 3.37) |
| CSRU | 2.06* (1.55 to 2.75) | 2.84* (1.87 to 4.32) | 3.56* (1.91 to 6.62) |
| Number of subjects | 2332 | 812 | 409 |
| AUC | 0.726 | 0.703 | 0.729 |
| Hosmer–Lemeshow p value | 0.03 | 0.17 | 0.16 |
Each column represents a separate propensity score model for a specific patient cohort. Treated patients received either fluids or vasoactive agents or both. Fluid-resuscitated patients received either only fluids or both fluids and vasoactive agents.
↵* Statistically significant.
↵† Reference.
AUC, area under the receiver operating characteristic curve; CCU, coronary care unit; CSRU, cardiac surgery recovery unit; HE, hypotensive episode; MAP, mean arterial pressure; MICU, medical intensive care unit; NA, not applicable (due to a lack of significant relationship with receipt of vasoactive therapy); SAPS, Simplified Acute Physiology Score; SICU, surgical intensive care unit.