Year | p value* | |||||
2006 (n=218) | 2007 (n=188) | 2008 (n=151) | 2009 (n=152) | 2010 (n=158) | ||
S aureus bacteraemia | ||||||
N (%) involving | <0.001 | |||||
MSSA | 156 (72) | 140 (74) | 100 (66) | 121 (80) | 142 (90) | |
MRSA | 62 (28) | 48 (26) | 51 (34) | 31 (20) | 16 (10) | |
Demographics | ||||||
Gender (female) (%) | 66 (30) | 62 (33) | 55 (36) | 55 (36) | 49 (30) | 0.603 |
Age (years) | 57 (22) | 56 (21) | 58 (22) | 56 (22) | 57 (20) | 0.744 |
Clinical characteristics | ||||||
Hospital associated (%) | 112 (51) | 108 (60) | 69 (46) | 75 (50) | 92 (58) | 0.750 |
Previous S aureus bacteraemia, any (%) | 10 (5) | 18 (10) | 19 (13) | 14 (10) | 12 (8) | 0.787 |
Previous MRSA colonisation or infection (%)† | 24 (39) | 24 (50) | 29 (57) | 16 (52) | 10 (63) | 0.056 |
Admission within past 12 months (%) | 134 (62) | 101 (54) | 92 (61) | 96 (63) | 99 (62) | 0.503 |
Outcomes | ||||||
30-day mortality (%) | 52 (24) | 39 (22) | 31 (21) | 27 (18) | 24 (15) | 0.013 |
Inhospital death (%) | 63 (29) | 45 (25) | 34 (23) | 34 (23) | 33 (21) | 0.045 |
Length of stay (days) | 19 (10–41) | 17 (7–36) | 27 (12–36) | 22 (12–44) | 19 (12–42) | 0.508 |
Readmission (≤14 days) (%) | 25 (17) | 19 (14) | 25 (22) | 31 (27) | 19 (16) | 0.291 |
All S aureus infection/colonisations | ||||||
N (%) involving‡ | <0.001 | |||||
MSSA | 1682 (72) | 1532 (75) | 1250 (74) | 1416 (83) | 1351 (90) | |
MRSA | 638 (28) | 510 (25) | 448 (26) | 289 (17) | 151 (10) |
↵* Linear and logistic regressions with month of study as sole explanatory variable.
↵† Data presented for MRSA bacteraemia only.
↵‡ Data available for adult non-obstetric patients 2006–2010. Counts represent non-duplicate isolates (one per patient per year).
MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive Staphylococcus aureus.