Table 7

Studies on weight loss conducted in general practice in the UK with 12-month follow-up

Study	Design	Intervention	Eligibility criteria	Weight (kg) at baseline, mean (SD)	Per cent (n/N) followed up at 12 months	Mean weight change (kg) at 12 months				Lost ≥5% baseline weight in the intervention group, % (95% CI)
Study	Design	Intervention	Eligibility criteria	Weight (kg) at baseline, mean (SD)	Per cent (n/N) followed up at 12 months	Intervention	Control	Difference (95% CI)	p Value
Moore et al, BMJ (2003)62	Cluster RCT	Trained GPs, nurses	BMI ≥30	–	67.7 (565/834)	−0.6	−0.9	1.0^*	0.5	–
McConnon et al, BMC (2007)55	RCT	Access to website	BMI ≥30; access to internet	98.4 (17.4)	59.3 (131/221)	−1.3	−1.9	0.6 (1.4 to 2.5)	0.56	22
Davies et al, DESMOND, BMJ (2007)19	RCT	Group sessions	Newly diagnosed type 2 diabetes	–	90.9 (729/824)	−3.0	−1.9	−1.0 (−1.9 to −0.12)	0.03	–
Ross et al, Counterweight, BJGP (2008)56	Audit	Trained practice nurses	BMI ≥30; BMI ≥28 with comorbidities	–	45.2 (642/1419)	−3.0	–	–	–	31 (27 to 34)
Ahern et al, Weight Watchers, BMC (2011)63	Audit	Weight Watchers meetings	BMI ≥30; NHS referral scheme	94.3 (IQR 83.7–107.7)	53	Median =−2.8	–	–	–	33
Jebb et al, Weight Watchers, Lancet (2011)57	RCT	Weight Watchers meetings	BMI 27–35 + 1 risk factor	86.7	57.5 (444/772)	−5.1	−2.2	−3.2 (−4.2 to −2.1)	<0.0001	47^†
Jolly et al, BMJ (2011)58	RCT	Various^‡	White BMI ≥30/≥28 + comorbidity; S Asian BMI ≥25/≥23 + comorbidity	91.7 (17.9)	70.5 (522/740)	−3.5	−1.1	−2.5 (−4.2 to −0.8)	0.02	31 (22 to 41)
CAMWEL	RCT	One-to-one sessions	BMI ≥25	92.3 (18.3)	57 (217/381)	−2.4	−1.3	−1.1 (−2.5 to 0.3)	0.13	34 (25 to 43)

↵* Difference between groups at 12 months.
↵† Based on graph in table 3.
↵‡ Range of commercial or primary care-led programmes, intervention results given for Weight Watchers.
BMI, body mass index; GP, general practitioners; RCT, randomised controlled trial.