MNI (peak) | Voxels (mm3) | White matter tract | Corresponding cortical area | FA value | λ1 (×103 mm2/s) | λ23 (×103 mm2/s) | |||||
x | y | z | COPD | Control | COPD | Control | COPD | Control | |||
1 | 10 | 16 | 240 | Fornix | Fornix | 0.248 (0.067) | 0.289 (0.073) | 2.586 (0.314) | 2.406 (0.0321) | 1.809 (0.295) | 1.577 (0.262)* |
−26 | −69 | 1 | 191 | Left lingual gyrus | 0.259 (0.042) | 0.283 (0.046) | 1.450 (0.240) | 1.370 (0.224) | 0.992 (0.185) | 0.896 (0.168)* | |
27 | −53 | 3 | 147 | Lingual gyrus | Right lingual gyrus | 0.265 (0.065) | 0.290 (0.056) | 1.381 (0.239) | 1.346 (0.227) | 0.955 (0.242) | 0.891 (0.215)* |
−23 | −19 | −24 | 77 | Parahippocampus | Left Parahippocampus | 0.268 (0.042) | 0.319 (0.046) | 1.234 (0.057) | 1.189 (0.052) | 0.869 (0.148) | 0.771 (0.125)* |
38 | −24 | −24 | 77 | Fusiform gyrus | Right fusiform gyrus | 0.231 (0.037) | 0.248 (0.046) | 1.053 (0.063) | 1.094 (0.073) | 0.774 (0.030) | 0.723 (0.032)* |
−10 | −91 | 17 | 204 | Optic radiation | Left occipital cortex | 0.234 (0.043) | 0.277 (0.041) | 1.037 (0.038) | 1.020 (0.031) | 0.752 (0.063) | 0.693 (0.051)* |
25 | −86 | −5 | 200 | Optic radiation | Right occipital cortex | 0.369 (0.099) | 0.409 (0.122) | 1.171 (0.014) | 1.177 (0.171) | 0.649 (0.057) | 0.601 (0.071)* |
−9 | −72 | 45 | 94 | SCR | Left precuneus | 0.283 (0.053) | 0.317 (0.056) | 1.099 (0.032) | 1.069 (0.041) | 0.726 (0.075) | 0.665 (0.065)* |
9 | −66 | 37 | 57 | SCR | Right precuneus | 0.251 (0.030) | 0.280 (0.044) | 1.044 (0.032) | 1.018 (0.023) | 0.868 (0.073) | 0.731 (0.084)* |
−15 | −51 | 62 | 57 | SCR | Left superior parietal lobule | 0.267 (0.043) | 0.294 (0.043) | 1.130 (0.051) | 1.082 (0.025) | 0.724 (0.039) | 0.671 (0.045)* |
16 | −45 | 64 | 66 | SCR | Right superior parietal lobule | 0.251 (0.043) | 0.294 (0.051) | 1.176 (0.117) | 1.107 (0.094) | 0.805 (0.056) | 0.762 (0.056)* |
−45 | −53 | 31 | 44 | SLF | Left supramarginal gyrus | 0.221 (0.027) | 0.239 (0.026) | 1.088 (0.020) | 1.076 (0.040) | 0.935 (0.090) | 0.873 (0.071)* |
37 | −68 | 21 | 63 | SLF | Right supramarginal gyrus | 0.220 (0.025) | 0.237 (0.025) | 1.116 (0.039) | 1.090 (0.052) | 0.773 (0.076) | 0.715 (0.007)* |
−48 | 0 | −16 | 43 | ILF | Left superior temporal gyrus | 0.244 (0.013) | 0.270 (0.021) | 1.060 (0.030) | 0.984 (0.015) | 0.758 (0.025) | 0.714 (0.037)* |
53 | −46 | −6 | 41 | ILF | Right middle temporal gyrus | 0.206 (0.016) | 0.241 (0.024) | 1.025 (0.016) | 1.006 (0.021) | 1.605 (0.167) | 1.340 (0.139)* |
Data are presented as means (SD).
*p<0.05.
COPD, chronic obstructive pulmonary disease; FA, fractional anisotropy; ILF, inferior longitudinal fasciculus; SCR, superior corona radiata; SLF, superior longitudinal fasciculus.