Baseline characteristics of the study patients according to gender and renal function
| Characteristics | Men (n=1412) | Women (n=558) | p Value* | ||||
| eGFR <60 ml/min (n=124) | eGFR ≥60 ml/min (n=1288) | p Value | eGFR <60 ml/min (n=138) | eGFR ≥60 ml/min (n=420) | p Value | ||
| Demographics | |||||||
| Age (year) | 75± (9) | 59± (12) | <0.001 | 78± (9) | 62± (13) | <0.001 | 0.005 |
| Body mass index | 25± (3.7) | 27± (3.8) | <0.001 | 25± (3.9) | 28± (10) | <0.001 | 0.19 |
| Risk factors | |||||||
| Current smoking | 33 (27%) | 560 (44%) | <0.001 | 25 (18%) | 179 (41%) | <0.001 | 0.098 |
| Hypertension | 48 (39%) | 360 (28%) | 0.012 | 62 (45%) | 144 (34%) | 0.025 | 0.31 |
| Hypercholesterolaemia | 19 (15%) | 264 (21%) | 0.17 | 21 (15%) | 99 (24%) | 0.04 | 0.98 |
| Diabetes mellitus | 20 (16%) | 126 (10%) | 0.027 | 29 (21%) | 62 (15%) | 0.085 | 0.31 |
| Clinical history | |||||||
| Myocardial infarction | 38 (36%) | 163 (13%) | <0.001 | 28 (22.0%) | 36 (9.3%) | <0.001 | 0.025 |
| Percutaneous coronary intervention | 25 (21%) | 126 (10%) | <0.001 | 8 (6.1%) | 31 (7.6%) | 0.55 | <0.001 |
| Coronary artery bypass grafting | 4 (3.5%) | 22 (1.8%) | 0.19 | 5 (3.8%) | 8 (2.0%) | 0.24 | 0.91 |
| Laboratory assessments | |||||||
| Troponin T (μg/l) | 0.04 (0.09–0.59) | 0.04 (0.04–0.20) | <0.001 | 0.15 (0.04–0.74) | 0.05 (0.04–0.26) | 0.001 | 0.15 |
| Glucose (mmol/l) | 8.9 (7.0–11.7) | 7.9 (6.7–9.5) | <0.001 | 9.1 (7.3–11.2) | 8.2 (6.9–10.1) | 0.003 | 0.72 |
| NTproBNP (ng/l) | 980 (340–3728) | 102 (50–341) | <0.001 | 1012 (307–5027) | 180 (99–627) | <0.001 | 0.81 |
| eGFR (ml/min) | 45± (12) | 116± (37) | – | 46 (10) | 105± (42) | – | – |
| Procedural characteristics | |||||||
| Systolic blood pressure, mm Hg | 123± (32) | 128± (27) | 0.11 | 135± (35) | 136± (30) | 0.59 | 0.006 |
| Heart rate, bpm | 80± (21) | 77± (17) | 0.21 | 79± (20) | 79± (19) | 0.79 | 0.92 |
| Shock | 14 (11.4%) | 37 (2.9%) | <0.001 | 10 (7.3%) | 15 (3.6%) | 0.074 | 0.26 |
| Anterior myocardial infarction | 58 (47%) | 502 (39%) | 0.17 | 49 (36%) | 172 (41%) | 0.26 | 0.06 |
| Time to treatment (min) | 223 (153–321) | 179 (125–269) | 0.013 | 201 (132–338) | 188 (141–276) | 0.49 | 0.07 |
Data are presented as absolute n (%), mean± (SD) or median (IQR).
↵* p Value for differences in characteristics between male and female patients with eGFR <60 ml/min.
CRP, C reactive protein; eGFR, estimated glomerular filtration rate; NTproBNP, N-terminal pro-brain natriuretic peptide.