Pre- and post-biopsy diagnosis and initial clinical management of the cohort
| Case | Clinical diagnosis (pre-biopsy) | PPI trial (pre- or post-biopsy) | pH study | Clinical diaxnosis post-biopsy |
| 1 | EO | Y (post) | Normal | EO |
| 2 | EO | Y (post) | Normal | EO |
| 3 | GORD | Y (pre) | Normal | EO |
| 4 | GORD | Y (pre) | ND | EO + GORD (OS) |
| 5 | GORD | Y (pre) | Normal | EO |
| 6 | ?GORD or non-ulcer dyspepsia | Y (post) | ND | EO |
| 7 | ?GORD | Y (pre) | Abnormal reflux index of 13% | EO + GORD (OS) |
| 8 | ?GORD | Y (pre) | Abnormal reflux index of 8.8% | EO + GORD (OS) |
| 9 | GORD | Y (pre) | Abnormal reflux index of 19.6% | EO + GORD (OS) |
| 10 | ?GORD | Y (pre) | Normal | EO + GORD |
| 11 | ?EO | Y (post) | ND | EO |
| 12 | ?GORD | Y (post) | Normal | EO |
| 13 | ?GORD | Y (pre) | Abnormal reflux index of 12.2% | EO + GORD (OS) |
| 14 | ?CMPA | Y (post) | Normal | EO |
| 15 | Achalasia of the cardia? EO | Y (pre) | ND | EO |
| 16 | Gastritis | Y (pre) | ND | EO |
| 17 | ?CMPA | Y (post) | Abnormal reflux index of 16.8% | EO + GORD (OS) |
| 18 | ?EO | Y (post) | Abnormal reflux index of 10.7% | EO + GORD (OS) |
| 19 | Likely CMPA | ND | ND | EO |
| 20 | Iron deficiency aneamia, ?coeliac disease | ND | ND | EO |
| 21 | ?EO | Y (pre) | ND | EO |
| 22 | ?GORD | Y (pre) | 173 reflux episodes/24 h (normal is <75) | EO + GORD (OS) |
| 23 | ?GORD | Y (pre) | Normal | EO |
| 24 | ?EO, ?GORD | Y (pre) | ND | EO |
CMPA, cow milk protein allergy; EO, eosinophilic oesophagitis; GORD, gastrooesophageal reflux disease; N, no; ND, not done; OS, overlap syndrome; PPI, proton pump inhibitor; Y, yes; ?, suspected clinical diagnosis.