Table 1

Demographic features, clinical history and endoscopic characteristics of the cohort children with oesophageal eosinophilia on histology

Case	Age	Sex	History	Endoscopy	Clinical Dx pre-biopsy result
1	23 m	M	Allergy, eczema, asthma, feeding problems	Corrugated, furrowing, trachealisation	EO
2	44 m	M	Dysphagia, intractable asthma	Corrugated, furrowing	EO
3	35 m	F	Reflux, food aversion	Furrowing, ridging	GORD
4	51 m	F	Failure to thrive, feeding problems, developmental delay, epilepsy	Normal	GORD
5	9 y	F	Poor weight gain, epigastric pain	Normal	GORD
6	19 m	M	No weight gain, poor appetite	Normal	?GORD or non-ulcer dyspepsia
7	39 m	F	Feeding problems, Russell–Silver syndrome, food aversion	White speckles, ?Candida oesophagitis	?GORD
8	15 y	M	Epigastric pain	Severe oesophagitis	?GORD
9	6 m	F	Vomiting and mucosy diarrhoea, asthma	No information available	GORD
10	15 y	M	Dysphagia, GORD	Normal	?GORD
11	23 m	M	Allergy, eczema, asthma, feeding problems	Furrowing, trachealisation	?EO
12	15 m	F	?GORD	Normal	?GORD
13	13 y	M	Heartburn, difficulty swallowing solids/liquids, family history of peptic ulcer	Furrowing	?GORD
14	16 m	F	?Cow milk protein intolerance	Normal	?CMPA
15	12 y	M	Asthma, eczema, food bolus obstruction	Furrowing	Achalasia of the cardia. ?EO
16	11 y	M	Food bolus obstruction	Normal, pre-pyloric ulcer	Gastritis
17	12 m	F	?CMPA	?Candida oesophagitis	?CMPA
18	14 y	F	Asthma, eczema	Furrowing	?EO
19	6 m	M	Failure to thrive, diarrhoea. ?protein-loosing enteropathy	Normal	Likely CMPA
20	42 m	F	Abdominal pain, ?coeliac disease, low IgA, poor weight gain	Normal	Iron deficiency aneamia, ?coeliac disease
21	14 y	M	Diarrhoea	Furrowing	?EO
22	10 y	F	Heartburn, reflux, vomiting	Trachealisation	?GORD
23	16 m	M	Vomiting	Oesophagitis	?GORD
24	11 m	M	Vomiting, failure to thrive, medulloblastoma in remission	Corrugated and furrowed oesophagus, trachealisation	?EO, ?GORD

CMPA, cow milk protein allergy; Dx, diagnosis; EO, eosinophilic oesophagitis; F, female; GORD, gastrooesophageal reflux disease; m, months; M, male; y, year?: suspected clinical diagnosis.