Clinical factors associated with depressive state (univariate logistic regression)
| Clinical factors | OR (95% CI) | p Value |
| Age (years) | 0.98 (0.96 to 1.00) | 0.060 |
| Female | 1.41 (0.63 to 3.14) | 0.41 |
| Time since onset (years) | 0.94 (0.89 to 1.00) | 0.041* |
| Age at onset (years) | 0.99 (0.97 to 1.01) | 0.51 |
| Thymectomy | 0.39 (0.18 to 1.24) | 0.27 |
| Thymoma | 0.91 (0.38 to 2.20) | 0.84 |
| QMG | 1.12 (1.05 to 1.19) | 0.0007* |
| Ocular QMG | 1.26 (1.05 to 1.52) | <0.012* |
| Bulbar QMG | 1.36 (0.94 to 1.98) | 0.10 |
| MG composite | 1.14 (1.08 to 1.20) | <0.0001* |
| MG-ADL | 1.21 (1.09 to 1.35) | 0.0003* |
| MGFA classification (worst) | 1.19 (0.88 to 1.62) | 0.26 |
| Current dose of PSL (mg/day) | 1.09 (1.04 to 1.15) | 0.0006* |
| Maximum dose of PSL (mg/day) | 1.00 (0.98 to 1.02) | 0.97 |
| Calcineurin inhibitors | 2.07 (1.01 to 4.27) | 0.048* |
| Crisis | 0.93 (0.26 to 3.29) | 0.91 |
| AChR-Ab positivity | 1.00 (1.00 to 1.01) | 0.28 |
| Kv 1.4-Ab positivity | 1.92 (0.70 to 5.26) | 0.20 |
| Titin-Ab positivity | 1.71 (0.93 to 3.14) | 0.10 |
| CSR (no case with BDI-II >21.5) | Not determined | Not determined |
| PR | 0.30 (0.04 to 2.28) | 0.24 |
| MM | 0.54 (0.24 to 1.24) | 0.15 |
| I | 1.24 (0.59 to 2.60) | 0.57 |
| U | 3.14 (1.46 to 6.77) | 0.004* |
| W | 5.93 (1.27 to 27.73) | 0.023* |
↵* Variables entered into multivariate logistic regression analysis (see the Results section in the text).
AChR-Ab, antibodies against acetylcholine receptor; CSR, complete stable remission; I, improved; Kv1.4, voltage-gated potassium channel 1.4; MG-ADL, MG activities of daily living scale; MG composite, MG composite scale; MGFA, Myasthenia Gravis Foundation of America; MM, minimal manifestations; MuSK, muscle-specific tyrosine kinase; PR, pharmacologic remission; PSL, prednisolone; QMG, MGFA quantitative MG score; U, unchanged; W, worse.