Table 4

Incidence of adverse events*

VariableViusid (n=50)Placebo (n=50)p Value†
No (%)No (%)
Asthenia12 (24)20 (40)0.08
Fatigue or malaise5 (10)13 (26)0.04
Muscle pain8 (16)16 (32)0.06
Anorexia5 (10)9 (18)0.24
Cramps11 (22)22 (44)0.02
Discomfort on the right upper quadrant7 (14)13 (26)0.13
Gingival bleeding5 (10)10 (20)0.16
Epistaxis5 (10)10 (20)0.16
Nausea5 (10)1 (2)0.12
Diarrhoea5 (5)1 (2)0.12
Sepsis7 (14)20 (40)<0.01
Hospitalisation9 (18)15 (30)0.24

  • ↵* The adverse events listed are those recorded in at least 5% of the patients in either study group.

  • ↵† p Values were calculated on the basis of the two-sided χ2.